Keerty Dinesh, Eaton Kevin, Haynes Elizabeth
Internal and Hospital Medicine, H. Lee Moffitt Cancer Center and Research Institute, Tampa, USA.
Internal Medicine, Moffitt Cancer Center, Tampa, USA.
Cureus. 2020 Jul 22;12(7):e9334. doi: 10.7759/cureus.9334.
Dapsone is a common medication that is utilized in the treatment of dermatological conditions, pneumocystis pneumonia, and toxoplasmosis. Methemoglobinemia is a known but rare complication of dapsone therapy that can result in cyanosis. We present a case of a patient on dapsone therapy who developed hypoxia due to methemoglobinemia. This case emphasizes the importance of knowledge of drugs likely to cause methemoglobinemia which requires clinicians to have a high degree of suspicion especially when the patient's oxygen saturation does not improve with treatment.
氨苯砜是一种常用药物，用于治疗皮肤病、肺孢子菌肺炎和弓形虫病。高铁血红蛋白血症是氨苯砜治疗已知但罕见的并发症，可导致发绀。我们报告一例接受氨苯砜治疗的患者因高铁血红蛋白血症发生缺氧的病例。该病例强调了了解可能导致高铁血红蛋白血症的药物的重要性，这要求临床医生高度怀疑，尤其是在患者经治疗后氧饱和度未改善时。
