所有获得性高铁血红蛋白血症患者都需要治疗吗？吸取的教训。
Do all patients with acquired methemoglobinemia need treatment? A lesson learnt.
作者信息
Khanal Raju, Karmacharya Paras, Pathak Ranjan, Poudel Dilli Ram, Ghimire Sushil, Alweis Richard
机构信息
Department of Internal Medicine, Reading Health System, West Reading, PA, USA;
Department of Internal Medicine, Reading Health System, West Reading, PA, USA.
出版信息
J Community Hosp Intern Med Perspect. 2015 Oct 19;5(5):29079. doi: 10.3402/jchimp.v5.29079. eCollection 2015.
Abstract
Acquired methemoglobinemia is a medical emergency, and its prompt recognition and treatment can avoid catastrophic complications including death. However, in mild asymptomatic cases without any comorbid conditions, it would be reasonable to simply observe and treat symptomatically to avoid severe treatment-related complications, especially in patients with suspected glucose-6-phosphate dehydrogenase (G6PD) deficiency. We present a case of mild methemoglobinemia in occult G6PD deficiency in which the patient developed hemolysis after treatment with intravenous methylene blue, requiring transfusion.
摘要
获得性高铁血红蛋白血症是一种医疗急症，及时识别和治疗可避免包括死亡在内的灾难性并发症。然而，对于轻度无症状且无任何合并症的病例，单纯观察并对症治疗是合理的，以避免严重的治疗相关并发症，尤其是在疑似葡萄糖-6-磷酸脱氢酶（G6PD）缺乏的患者中。我们报告一例隐匿性G6PD缺乏导致的轻度高铁血红蛋白血症病例，该患者在接受静脉注射亚甲蓝治疗后发生溶血，需要输血。
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