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香港的第二次髋部骨折——发病率、人口统计学特征及死亡率

Second hip fracture in Hong Kong - Incidence, demographics, and mortality.

作者信息

Ho Angela Wing Hang, Wong Sze Hung

机构信息

Department of Orthopaedics and Traumatology, Caritas Medical Centre, Hong Kong.

出版信息

Osteoporos Sarcopenia. 2020 Jun;6(2):71-74. doi: 10.1016/j.afos.2020.05.004. Epub 2020 Jun 18.

DOI:10.1016/j.afos.2020.05.004
PMID:32715097
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7374255/
Abstract

OBJECTIVES

The aim of this study is to investigate the incidence of second hip fractures after a previous hip fracture and subsequent mortality in Chinese men and women.

METHODS

Data of patients aged 65 years or above with operatively treated hip fracture in the years 2000-2011 in Hong Kong were retrieved from Hospital Authority clinical database. During the follow-up period, second contralateral operatively treated hip fractures were identified. The incidence of a second fracture was determined using survival analysis.

RESULTS

A total of 2399 second hip fractures were identified. The cumulative incidence of a second fracture was 1.24% at 1 year and 4.42% at 5 years with 60% of second fractures occurring within 4 years after the initial fracture. In cox regression model, a higher incidence was observed as age increased (hazard ratio [HR], 1.08; P < 0.001). The cumulative mortality at 1 and 5 years after a second fracture was 16.9% and 54.8%, respectively. The median survival after single fracture was 4.9 years, while after a second fracture it was 3.8 years (P < 0.05). Lower survival was observed after the second fracture (HR, 5.44; P < 0.05), in men (HR, 1.91; P < 0.05) and older patients (HR, 1.061; P < 0.05).

CONCLUSIONS

Patients with history of hip fracture are at high risk to develop a second fracture. Initiation of treatment and fragility fracture prevention program after primary hip fracture should be started in order to reduce second fracture incidence and related mortality.

摘要

目的

本研究旨在调查中国男性和女性既往髋部骨折后再次发生髋部骨折的发生率及随后的死亡率。

方法

从医院管理局临床数据库中检索2000年至2011年在香港接受手术治疗的65岁及以上髋部骨折患者的数据。在随访期间,确定对侧再次接受手术治疗的髋部骨折情况。使用生存分析确定再次骨折的发生率。

结果

共识别出2399例再次髋部骨折。再次骨折的累积发生率在1年时为1.24%,5年时为4.42%,其中60%的再次骨折发生在初次骨折后的4年内。在Cox回归模型中,随着年龄的增加,再次骨折的发生率更高(风险比[HR],1.08;P<0.001)。再次骨折后1年和5年的累积死亡率分别为16.9%和54.8%。单次骨折后的中位生存期为4.9年,而再次骨折后为3.8年(P<0.05)。再次骨折后(HR,5.44;P<0.05)、男性(HR,1.91;P<0.05)和老年患者(HR,1.061;P<0.05)的生存期较低。

结论

有髋部骨折病史的患者发生再次骨折的风险很高。应在初次髋部骨折后启动治疗和脆性骨折预防计划,以降低再次骨折的发生率及相关死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/333b/7374255/b67d9f48e19d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/333b/7374255/733b1477bc8c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/333b/7374255/b67d9f48e19d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/333b/7374255/733b1477bc8c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/333b/7374255/b67d9f48e19d/gr2.jpg

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2
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Bone. 2013 Jan;52(1):493-7. doi: 10.1016/j.bone.2012.09.009. Epub 2012 Sep 18.
3
Age-specific incidence of first and second fractures of the hip.髋部首次和二次骨折的年龄特异性发病率。
Geriatric nutritional risk index as the prognostic factor in older patients with fragility hip fractures.
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Osteoporos Int. 2023 Jul;34(7):1207-1221. doi: 10.1007/s00198-023-06753-3. Epub 2023 Apr 17.
4
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J Bone Miner Res. 2023 Feb;38(2):278-287. doi: 10.1002/jbmr.4760. Epub 2022 Dec 30.
5
Risk factors for contralateral hip refractures in patients aged over 80 years with intertrochanteric femoral fractures.80岁以上股骨转子间骨折患者对侧髋部骨折的危险因素。
Front Surg. 2022 Sep 13;9:924585. doi: 10.3389/fsurg.2022.924585. eCollection 2022.
6
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7
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J Bone Metab. 2020 Nov;27(4):281-290. doi: 10.11005/jbm.2020.27.4.281. Epub 2020 Nov 30.
J Bone Joint Surg Br. 2010 Feb;92(2):258-61. doi: 10.1302/0301-620X.92B2.23108.
4
Ten-year fracture probability in Hong Kong Southern Chinese according to age and BMD femoral neck T-scores.根据年龄和股骨颈 T 评分,香港华南人群的 10 年骨折概率。
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8
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9
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Osteoporos Int. 2005 Oct;16(10):1239-46. doi: 10.1007/s00198-005-1835-2. Epub 2005 Feb 24.
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