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髋部首次和二次骨折的年龄特异性发病率。

Age-specific incidence of first and second fractures of the hip.

作者信息

Lawrence T M, Wenn R, Boulton C T, Moran C G

机构信息

Department of Trauma and Orthopaedics University Hospitals, Queens Medical Centre, Nottingham University Hospitals Trust, Nottingham NG7 2UH, UK.

出版信息

J Bone Joint Surg Br. 2010 Feb;92(2):258-61. doi: 10.1302/0301-620X.92B2.23108.

Abstract

We determined the age-specific incidence of a second fracture of the hip and compared it with that of a primary fracture in a study population drawn from 6331 patients admitted to Nottingham University Hospital with a primary fracture of the hip over a period of 8.5 years. The incidence of a second fracture was determined using survival analysis. The mean age-specific incidence rates of primary hip fracture were calculated using census data. The overall incidence of a second fracture was 2.7% at one year and 7.8% at 8.5 years. That of a primary fracture was 50 per 100 000 in women aged 55 to 64 years rising to 3760 in those aged 84 years and over. The incidence of a second fracture in women aged 55 to 64 years was 2344 per 100 000. Patients of this age had a relative risk of 45 (95% confidence interval 13 to 155) for further fracture when compared with the population at risk of a first fracture. The incidence of a second fracture in women aged > 84 years was 2451 per 100 000 (relative risk 0.7, 95% confidence interval 0.5 to 0.9). A similar trend was seen in men. Patients sustaining a primary fracture of the hip between the ages of 55 and 64 years have a much greater risk of further fracture than the normal population, whereas those over 84 years have a similar risk. These findings have important implications for the provision of fracture prevention services in primary and secondary care.

摘要

我们在一项研究中确定了髋部二次骨折的年龄特异性发病率,并将其与初次骨折的发病率进行了比较。该研究人群来自于8.5年间入住诺丁汉大学医院的6331例初次髋部骨折患者。二次骨折的发病率通过生存分析来确定。初次髋部骨折的年龄特异性发病率均值利用人口普查数据进行计算。二次骨折的总体发病率在1年时为2.7%,在8.5年时为7.8%。初次骨折的发病率在55至64岁女性中为每10万人50例,在84岁及以上女性中升至每10万人3760例。55至64岁女性二次骨折的发病率为每10万人2344例。与有初次骨折风险的人群相比,这个年龄段的患者再次骨折的相对风险为45(95%置信区间为13至155)。84岁以上女性二次骨折的发病率为每10万人2451例(相对风险0.7,95%置信区间0.5至0.9)。男性中也观察到了类似趋势。55至64岁发生初次髋部骨折的患者再次骨折的风险比正常人群高得多,而84岁以上患者的风险则与之相似。这些发现对于在初级和二级医疗保健中提供骨折预防服务具有重要意义。

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