European Molecular Biology Laboratory, Genome Biology Unit, 69117 Heidelberg, Germany.
Candidate for Joint PhD Between EMBL and Heidelberg University, Faculty of Biosciences, 69120 Heidelberg, Germany.
Bioinformatics. 2021 Apr 20;37(3):431-433. doi: 10.1093/bioinformatics/btaa682.
Rtpca is an R package implementing methods for inferring protein-protein interactions (PPIs) based on thermal proteome profiling experiments of a single condition or in a differential setting via an approach called thermal proximity coaggregation. It offers user-friendly tools to explore datasets for their PPI predictive performance and easily integrates with available R packages.
Rtpca is available from Bioconductor (https://bioconductor.org/packages/Rtpca).
Supplementary data are available at Bioinformatics online.
Rtpca 是一个 R 包，它实现了基于单一条件的热蛋白质组谱实验或通过称为热接近共沉淀的方法在差异条件下推断蛋白质-蛋白质相互作用 (PPIs) 的方法。它提供了用户友好的工具来探索数据集的 PPI 预测性能，并与可用的 R 包轻松集成。
Rtpca 可从 Bioconductor（https://bioconductor.org/packages/Rtpca）获得。
补充数据可在 Bioinformatics 在线获得。
