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从紧急医疗服务数据看 COVID-19 期间阿片类药物过量的信号增加。

Signal of increased opioid overdose during COVID-19 from emergency medical services data.

机构信息

Department of Biostatistics, University of Kentucky, Lexington, KY, United States; Kentucky Injury Prevention and Research Center, University of Kentucky, Lexington, KY, United States.

Kentucky Injury Prevention and Research Center, University of Kentucky, Lexington, KY, United States.

出版信息

Drug Alcohol Depend. 2020 Sep 1;214:108176. doi: 10.1016/j.drugalcdep.2020.108176. Epub 2020 Jul 10.

Abstract

BACKGROUND

Individuals with opioid use disorder may be at heightened risk of opioid overdose during the COVID-19 period of social isolation, economic distress, and disrupted treatment services delivery. This study evaluated changes in daily number of Kentucky emergency medical services (EMS) runs for opioid overdose between January 14, 2020 and April 26, 2020.

METHODS

We evaluated the statistical significance of the changes in the average daily EMS opioid overdose runs in the 52 days before and after the COVID-19 state of emergency declaration, March 6, 2020.

RESULTS

Kentucky EMS opioid overdose daily runs increased after the COVID-19 state emergency declaration. In contrast, EMS daily runs for other conditions leveled or declined. There was a 17% increase in the number of EMS opioid overdose runs with transportation to an emergency department (ED), a 71% increase in runs with refused transportation, and a 50% increase in runs for suspected opioid overdoses with deaths at the scene. The average daily EMS opioid overdose runs with refused transportation increased significantly, doubled to an average of 8 opioid overdose patients refusing transportation every day during the COVID-19-related study period.

CONCLUSIONS

This Kentucky-specific study provides empirical evidence for concerns that opioid overdoses are rising during the COVID-19 pandemic and calls for sharing of observations and analyses from different regions and surveillance systems with timely data collection (e.g., EMS data, syndromic surveillance data for ED visits) to improve our understanding of the situation, inform proactive response, and prevent another big wave of opioid overdoses in our communities.

摘要

背景

在 COVID-19 社交隔离、经济困境和治疗服务中断期间,患有阿片类药物使用障碍的个体可能面临更高的阿片类药物过量风险。本研究评估了 2020 年 1 月 14 日至 2020 年 4 月 26 日期间,肯塔基州急诊医疗服务(EMS)因阿片类药物过量而进行的日常运行次数的变化。

方法

我们评估了 COVID-19 紧急状态声明后 52 天(2020 年 3 月 6 日)前后,每日 EMS 阿片类药物过量运行的平均值变化的统计学意义。

结果

肯塔基州 EMS 阿片类药物过量每日运行量在 COVID-19 州紧急状态宣布后增加。相比之下,EMS 对其他疾病的日常运行量持平或下降。与转运到急诊部(ED)的 EMS 阿片类药物过量运行次数增加了 17%,拒绝转运的运行次数增加了 71%,疑似阿片类药物过量导致现场死亡的运行次数增加了 50%。拒绝转运的 EMS 阿片类药物过量每日运行次数显著增加,在与 COVID-19 相关的研究期间,每天拒绝转运的平均阿片类药物过量患者增加到 8 人。

结论

这项针对肯塔基州的具体研究提供了实证证据,表明人们担心在 COVID-19 大流行期间阿片类药物过量正在上升,并呼吁从不同地区和监测系统共享观察结果和分析,并及时收集数据(例如,EMS 数据、ED 就诊的症状监测数据),以增进我们对这种情况的了解,主动应对,并防止我们社区再次出现阿片类药物过量的浪潮。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b03/7351024/25034e2d1fc0/gr1_lrg.jpg

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