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本文引用的文献

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Signal of increased opioid overdose during COVID-19 from emergency medical services data.从紧急医疗服务数据看 COVID-19 期间阿片类药物过量的信号增加。
Drug Alcohol Depend. 2020 Sep 1;214:108176. doi: 10.1016/j.drugalcdep.2020.108176. Epub 2020 Jul 10.
2
An overdose surge will compound the COVID-19 pandemic if urgent action is not taken.如果不采取紧急行动,药物过量潮将使 COVID-19 大流行更加严重。
Nat Med. 2020 Jun;26(6):819-820. doi: 10.1038/s41591-020-0898-0.
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Drug Overdose Deaths in the United States, 1999-2018.美国 1999-2018 年药物过量死亡人数。
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An Epidemic in the Midst of a Pandemic: Opioid Use Disorder and COVID-19.大流行中的疫情:阿片类药物使用障碍和 COVID-19。
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Identification and Description of Non-Fatal Opioid Overdoses using Rhode Island EMS Data, 2016-2018.利用罗德岛紧急医疗服务数据对2016 - 2018年非致命性阿片类药物过量使用情况进行识别与描述
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The triple wave epidemic: Supply and demand drivers of the US opioid overdose crisis.三重波流行疫情:美国阿片类药物过量危机的供需驱动因素。
Int J Drug Policy. 2019 Sep;71:183-188. doi: 10.1016/j.drugpo.2019.01.010. Epub 2019 Feb 2.
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Drug and Opioid-Involved Overdose Deaths - United States, 2013-2017.药物和阿片类药物滥用相关的过量死亡-美国,2013-2017 年。
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8
Changing dynamics of the drug overdose epidemic in the United States from 1979 through 2016.美国 1979 年至 2016 年期间药物过量流行的动态变化。
Science. 2018 Sep 21;361(6408). doi: 10.1126/science.aau1184.
9
Vital Signs: Trends in Emergency Department Visits for Suspected Opioid Overdoses - United States, July 2016-September 2017.生命体征:2016年7月至2017年9月美国疑似阿片类药物过量急诊就诊趋势
MMWR Morb Mortal Wkly Rep. 2018 Mar 9;67(9):279-285. doi: 10.15585/mmwr.mm6709e1.
10
Measuring a Crisis: Questioning the Use of Naloxone Administrations as a Marker for Opioid Overdoses in a Large U.S. EMS System.衡量一场危机:质疑在美国一个大型紧急医疗服务系统中使用纳洛酮给药作为阿片类药物过量的标志物。
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紧急医疗服务和症状监测:与传统监测的比较及其对及时性的影响。

Emergency Medical Services and Syndromic Surveillance: A Comparison With Traditional Surveillance and Effects on Timeliness.

机构信息

4530 Kentucky Injury Prevention and Research Center, University of Kentucky, Lexington, KY, USA.

50880 Institute for Biomedical Informatics, University of Kentucky, Lexington, KY, USA.

出版信息

Public Health Rep. 2021 Nov-Dec;136(1_suppl):72S-79S. doi: 10.1177/00333549211018673.

DOI:10.1177/00333549211018673
PMID:34726974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8573779/
Abstract

OBJECTIVE

Traditional public health surveillance of nonfatal opioid overdose relies on emergency department (ED) billing data, which can be delayed substantially. We compared the timeliness of 2 new data sources for rapid drug overdose surveillance-emergency medical services (EMS) and syndromic surveillance-with ED billing data.

METHODS

We used data on nonfatal opioid overdoses in Kentucky captured in EMS, syndromic surveillance, and ED billing systems during 2018-2019. We evaluated the time-series relationships between EMS and ED billing data and syndromic surveillance and ED billing data by calculating cross-correlation functions, controlling for influences of autocorrelations. A case example demonstrates the usefulness of EMS and syndromic surveillance data to monitor rapid changes in opioid overdose encounters in Kentucky during the COVID-19 epidemic.

RESULTS

EMS and syndromic surveillance data showed moderate-to-strong correlation with ED billing data on a lag of 0 ( = 0.694; 95% CI, 0.579-0.782; = 9.73; df = 101; < .001; and = 0.656; 95% CI, 0.530-0.754; = 8.73; df = 101; < .001; respectively) at the week-aggregated level. After the COVID-19 emergency declaration, EMS and syndromic surveillance time series had steep increases in April and May 2020, followed by declines from June through September 2020. The ED billing data were available for analysis 3 months after the end of a calendar quarter but closely followed the trends identified by the EMS and syndromic surveillance data.

CONCLUSION

Data from EMS and syndromic surveillance systems can be reliably used to monitor nonfatal opioid overdose trends in Kentucky in near-real time to inform timely public health response.

摘要

目的

传统的非致命类阿片药物过量公共卫生监测依赖于急诊部门(ED)计费数据,而这些数据可能会有较大延迟。我们比较了两种新的快速药物过量监测数据源——紧急医疗服务(EMS)和症状监测——与 ED 计费数据的及时性。

方法

我们使用了 2018-2019 年肯塔基州 EMS、症状监测和 ED 计费系统中捕获的非致命类阿片药物过量数据。我们通过计算交叉相关函数,控制自相关的影响,评估了 EMS 和 ED 计费数据以及症状监测和 ED 计费数据之间的时间序列关系。通过一个案例研究,展示了 EMS 和症状监测数据在监测 COVID-19 流行期间肯塔基州类阿片药物过量事件的快速变化方面的有用性。

结果

在滞后 0 周时,EMS 和症状监测数据与 ED 计费数据具有中等至强相关性( = 0.694;95%CI,0.579-0.782; = 9.73;df = 101; <.001; = 0.656;95%CI,0.530-0.754; = 8.73;df = 101; <.001),在周汇总水平上。在 COVID-19 紧急声明后,EMS 和症状监测时间序列在 2020 年 4 月和 5 月急剧上升,随后在 2020 年 6 月至 9 月下降。ED 计费数据可在一个日历季度结束后 3 个月进行分析,但密切跟踪 EMS 和症状监测数据确定的趋势。

结论

EMS 和症状监测系统的数据可以可靠地用于监测肯塔基州非致命类阿片药物过量趋势,以便及时做出公共卫生反应。