• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

全国居家令对 COVID-19 大流行第一波期间疑似阿片类药物过量急诊就诊的影响。

The impact of the national stay-at-home order on emergency department visits for suspected opioid overdose during the first wave of the COVID-19 pandemic.

机构信息

Department of Geography and Division of Epidemiology, The Ohio State University, Columbus, OH, United States.

Department of Biostatistics, University of Kentucky, Lexington, KY, United States.

出版信息

Drug Alcohol Depend. 2021 Nov 1;228:108977. doi: 10.1016/j.drugalcdep.2021.108977. Epub 2021 Aug 28.

DOI:10.1016/j.drugalcdep.2021.108977
PMID:34598100
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8397502/
Abstract

BACKGROUND

Although national syndromic surveillance data reported declines in emergency department (ED) visits after the declaration of the national stay-at-home order for COVID-19, little is known whether these declines were observed for suspected opioid overdose.

METHODS

This interrupted time series study used syndromic surveillance data from four states participating in the HEALing Communities Study: Kentucky, Massachusetts, New York, and Ohio. All ED encounters for suspected opioid overdose (n = 48,301) occurring during the first 31 weeks of 2020 were included. We examined the impact of the national public health emergency for COVID-19 (declared on March 14, 2020) on trends in ED encounters for suspected opioid overdose.

RESULTS

Three of four states (Massachusetts, New York and Ohio) experienced a statistically significant immediate decline in the rate of ED encounters for suspected opioid overdose (per 100,000) after the nationwide public health emergency declaration (MA: -0.99; 95 % CI: -1.75, -0.24; NY: -0.10; 95 % CI, -0.20, 0.0; OH: -0.33, 95 % CI: -0.58, -0.07). After this date, Ohio and Kentucky experienced a sustained rate of increase for a 13-week period. New York experienced a decrease in the rate of ED encounters for a 10-week period, after which the rate began to increase. In Massachusetts after a significant immediate decline in the rate of ED encounters, there was no significant difference in the rate of change for a 6-week period, followed by an immediate increase in the ED rate to higher than pre-COVID levels.

CONCLUSIONS

The heterogeneity in the trends in ED encounters between the four sites show that the national stay-at-home order had a differential impact on opioid overdose ED presentation in each state.

摘要

背景

尽管国家综合征监测数据报告在宣布 COVID-19 全国居家令后,急诊科 (ED) 就诊量有所下降,但对于疑似阿片类药物过量的下降情况却知之甚少。

方法

这项中断时间序列研究使用了参与 HEALing 社区研究的四个州的综合征监测数据:肯塔基州、马萨诸塞州、纽约州和俄亥俄州。所有在 2020 年的前 31 周内发生的疑似阿片类药物过量的 ED 就诊(n=48301)均包括在内。我们研究了 COVID-19 国家公共卫生紧急情况(2020 年 3 月 14 日宣布)对疑似阿片类药物过量的 ED 就诊趋势的影响。

结果

在全国公共卫生紧急情况宣布后,四个州中的三个州(马萨诸塞州、纽约州和俄亥俄州)的疑似阿片类药物过量的 ED 就诊率(每 10 万人)立即出现了统计学上的显著下降(MA:-0.99;95%CI:-1.75,-0.24;NY:-0.10;95%CI,-0.20,0.0;OH:-0.33,95%CI:-0.58,-0.07)。在此日期之后,俄亥俄州和肯塔基州经历了持续的 13 周的增长率。纽约州经历了 10 周的 ED 就诊率下降,之后该比率开始上升。在马萨诸塞州,ED 就诊率立即显著下降后,在 6 周的时间内,变化率没有显著差异,随后 ED 就诊率立即增加到高于 COVID-19 前的水平。

结论

四个地点的 ED 就诊趋势的异质性表明,全国居家令对每个州的阿片类药物过量 ED 表现产生了不同的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/12dc2df492eb/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/a586e942b57b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/22c944d0e4fc/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/12dc2df492eb/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/a586e942b57b/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/22c944d0e4fc/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4781/8397502/12dc2df492eb/gr3_lrg.jpg

相似文献

1
The impact of the national stay-at-home order on emergency department visits for suspected opioid overdose during the first wave of the COVID-19 pandemic.全国居家令对 COVID-19 大流行第一波期间疑似阿片类药物过量急诊就诊的影响。
Drug Alcohol Depend. 2021 Nov 1;228:108977. doi: 10.1016/j.drugalcdep.2021.108977. Epub 2021 Aug 28.
2
The effect of sample site and collection procedure on identification of SARS-CoV-2 infection.样本采集部位和采集程序对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染鉴定的影响。
Cochrane Database Syst Rev. 2024 Dec 16;12(12):CD014780. doi: 10.1002/14651858.CD014780.
3
Rapid, point-of-care antigen tests for diagnosis of SARS-CoV-2 infection.用于 SARS-CoV-2 感染诊断的快速、即时抗原检测。
Cochrane Database Syst Rev. 2022 Jul 22;7(7):CD013705. doi: 10.1002/14651858.CD013705.pub3.
4
Do heroin overdose patients require observation after receiving naloxone?海洛因过量患者在接受纳洛酮治疗后需要观察吗?
Clin Toxicol (Phila). 2017 Feb;55(2):81-87. doi: 10.1080/15563650.2016.1253846. Epub 2016 Nov 16.
5
Regional Variation in Opioid-Related Emergency Medical Services Transfers During the COVID-19 Pandemic: An Interrupted Time Series Analysis.新冠疫情期间阿片类药物相关急救医疗服务转院的区域差异:一项中断时间序列分析。
Subst Use Addctn J. 2024 Jan;45(1):74-80. doi: 10.1177/29767342231208823.
6
Antibody tests for identification of current and past infection with SARS-CoV-2.抗体检测用于鉴定 SARS-CoV-2 的现症感染和既往感染。
Cochrane Database Syst Rev. 2022 Nov 17;11(11):CD013652. doi: 10.1002/14651858.CD013652.pub2.
7
Physical interventions to interrupt or reduce the spread of respiratory viruses.物理干预措施以阻断或减少呼吸道病毒的传播。
Cochrane Database Syst Rev. 2023 Jan 30;1(1):CD006207. doi: 10.1002/14651858.CD006207.pub6.
8
Emergency Department Peer Support Program and Patient Outcomes After Opioid Overdose.急诊室同伴支持计划对阿片类药物过量患者结局的影响。
JAMA Netw Open. 2024 Mar 4;7(3):e243614. doi: 10.1001/jamanetworkopen.2024.3614.
9
Signs and symptoms to determine if a patient presenting in primary care or hospital outpatient settings has COVID-19.在基层医疗机构或医院门诊环境中,如果患者出现以下症状和体征,可判断其是否患有 COVID-19。
Cochrane Database Syst Rev. 2022 May 20;5(5):CD013665. doi: 10.1002/14651858.CD013665.pub3.
10
Communities That HEAL Intervention and Mortality Including Polysubstance Overdose Deaths: A Randomized Clinical Trial.社区康复干预与死亡率:包括多药物过量死亡的随机临床试验。
JAMA Netw Open. 2024 Oct 1;7(10):e2440006. doi: 10.1001/jamanetworkopen.2024.40006.

引用本文的文献

1
States' COVID-19 policy contexts and suicide rates among US working-age adults.美国各州的新冠疫情政策背景与美国劳动年龄成年人的自杀率
Health Aff Sch. 2025 Mar 15;3(3):qxaf024. doi: 10.1093/haschl/qxaf024. eCollection 2025 Mar.
2
Changes in substance use, recovery, and quality of life during the initial phase of the COVID-19 pandemic.在 COVID-19 大流行的初始阶段,物质使用、恢复和生活质量的变化。
PLoS One. 2024 May 22;19(5):e0300848. doi: 10.1371/journal.pone.0300848. eCollection 2024.
3
State COVID-19 Policies and Drug Overdose Mortality Among Working-Age Adults in the United States, 2020.

本文引用的文献

1
Emergency Department Visits for Nonfatal Opioid Overdose During the COVID-19 Pandemic Across Six US Health Care Systems.在六个美国医疗保健系统中,COVID-19 大流行期间非致命类阿片药物过量的急诊就诊情况。
Ann Emerg Med. 2022 Feb;79(2):158-167. doi: 10.1016/j.annemergmed.2021.03.013. Epub 2021 Mar 19.
2
How emergency department visits for substance use disorders have evolved during the early COVID-19 pandemic.在 COVID-19 大流行早期,急诊就诊治疗物质使用障碍的情况是如何演变的。
J Subst Abuse Treat. 2021 Oct;129:108391. doi: 10.1016/j.jsat.2021.108391. Epub 2021 Apr 9.
3
Trends in US Emergency Department Visits for Mental Health, Overdose, and Violence Outcomes Before and During the COVID-19 Pandemic.
美国 2020 年工作年龄段成年人的州 COVID-19 政策与药物过量死亡率。
Am J Public Health. 2024 Jul;114(7):714-722. doi: 10.2105/AJPH.2024.307621. Epub 2024 May 2.
4
The impact of the COVID-19 pandemic on the use of restraint and seclusion interventions in Ontario emergency departments: A population-based study.新冠疫情对安大略省急诊部门约束和隔离干预措施使用的影响:一项基于人群的研究。
PLoS One. 2024 Apr 16;19(4):e0302164. doi: 10.1371/journal.pone.0302164. eCollection 2024.
5
An Approach to Enhancing Medication Treatment for Opioid Use Disorder in the HEALing Communities Study.一种增强 HEALing 社区研究中阿片类药物使用障碍药物治疗的方法。
Psychiatr Serv. 2024 Jun 1;75(6):580-588. doi: 10.1176/appi.ps.20230159. Epub 2024 Feb 13.
6
Interrupted time series analysis of drug overdose fatalities in service-related industries versus non-service-related industries during the COVID-19 pandemic, 2018-2021.2018-2021 年 COVID-19 大流行期间,服务行业与非服务行业药物过量死亡的中断时间序列分析。
Inj Prev. 2023 Nov 27;29(6):511-518. doi: 10.1136/ip-2023-044894.
7
An interrupted time series analysis of trends in opioid-related emergency department visits from pre-COVID-19 pandemic to pandemic, from the Canadian Hospitals Injury Reporting and Prevention Program.一项利用加拿大医院伤害报告和预防计划,对新冠大流行前后阿片类药物相关急诊就诊趋势的中断时间序列分析。
BMC Public Health. 2023 Aug 4;23(1):1483. doi: 10.1186/s12889-023-16414-z.
8
Public mental health during and after the SARS-CoV-2 pandemic: Opportunities for intervention emotional self-efficacy and resilience.新型冠状病毒肺炎疫情期间及之后的公众心理健康:干预机会、情绪自我效能感和心理韧性。
Front Psychol. 2023 Jan 23;14:1016337. doi: 10.3389/fpsyg.2023.1016337. eCollection 2023.
9
Psychiatric Emergencies in Los Angeles County During, and After, Initial COVID-19 Societal Restrictions: An Interrupted Time-Series Analysis.洛杉矶县在首次实施 COVID-19 社会限制期间和之后的精神科急症:一项中断时间序列分析。
Community Ment Health J. 2023 May;59(4):622-630. doi: 10.1007/s10597-022-01043-4. Epub 2022 Dec 12.
10
Has the United States Reached a Plateau in Overdoses Caused by Synthetic Opioids After the Onset of the COVID-19 Pandemic? Examination of Centers for Disease Control and Prevention Data to November 2021.在新冠疫情爆发后,美国由合成阿片类药物导致的过量用药情况是否已达到平稳状态?对疾病控制与预防中心截至2021年11月的数据进行的审查。
Front Psychiatry. 2022 Jul 7;13:947603. doi: 10.3389/fpsyt.2022.947603. eCollection 2022.
美国在新冠疫情前后因心理健康、药物过量和暴力而前往急诊部就诊的趋势。
JAMA Psychiatry. 2021 Apr 1;78(4):372-379. doi: 10.1001/jamapsychiatry.2020.4402.
4
Fentanyl and fentanyl analogs in the illicit stimulant supply: Results from U.S. drug seizure data, 2011-2016.芬太尼和芬太尼类似物在非法兴奋剂供应中的情况:来自美国缉获药物数据的结果,2011-2016 年。
Drug Alcohol Depend. 2021 Jan 1;218:108416. doi: 10.1016/j.drugalcdep.2020.108416. Epub 2020 Nov 23.
5
Overdose-Related Cardiac Arrests Observed by Emergency Medical Services During the US COVID-19 Epidemic.美国 COVID-19 疫情期间,急救医疗服务中心观察到的与过量用药相关的心脏骤停事件。
JAMA Psychiatry. 2021 May 1;78(5):562-564. doi: 10.1001/jamapsychiatry.2020.4218.
6
The HEALing (Helping to End Addiction Long-term ) Communities Study: Protocol for a cluster randomized trial at the community level to reduce opioid overdose deaths through implementation of an integrated set of evidence-based practices.HEALing(帮助长期戒毒)社区研究:一项在社区层面进行的群组随机试验方案,通过实施一套综合的基于证据的实践来减少阿片类药物过量死亡。
Drug Alcohol Depend. 2020 Dec 1;217:108335. doi: 10.1016/j.drugalcdep.2020.108335. Epub 2020 Oct 17.
7
Ambulance Calls for Substance-Related Issues Before and After COVID-19.救护车在 COVID-19 前后因物质相关问题的呼叫。
Prehosp Emerg Care. 2021 Nov-Dec;25(6):768-776. doi: 10.1080/10903127.2020.1845420. Epub 2020 Dec 15.
8
Naloxone Use by Emergency Medical Services During the COVID-19 Pandemic: A National Survey.《COVID-19 大流行期间急救医疗服务机构使用纳洛酮情况:全国性调查》。
J Addict Med. 2020 Dec;14(6):e369-e371. doi: 10.1097/ADM.0000000000000746.
9
The Opioid Epidemic Within the COVID-19 Pandemic: Drug Testing in 2020.新冠疫情下的阿片类药物流行:2020 年的药物检测。
Popul Health Manag. 2021 Feb;24(S1):S43-S51. doi: 10.1089/pop.2020.0230. Epub 2020 Oct 8.
10
Substance use and related harms in the context of COVID-19: a conceptual model.在 COVID-19 背景下的物质使用及相关危害:概念模型。
Health Promot Chronic Dis Prev Can. 2020 Dec 9;40(11-12):342-349. doi: 10.24095/hpcdp.40.11/12.03. Epub 2020 Sep 16.