Sobiech K A, Madej J A
Department of Biochemistry, Academy of Physical Education, Wrocław.
Pol Arch Weter. 1988;28(3-4):17-21.
The activity of cobalt-activated acylase was determined in the serum of mice with transplantable leukemia (P 388, L 1210 standard, L 1210/ara-C, L 1210/CH3-G, plasmocytoma ADJPC-5, lymphoma AKSL-4 and natural leukemia in mice NZB). A statistically significant increase in enzyme activity in all leukemias except lymphatic leukemia has been demonstrated. The results suggest possibility of using the enzymatic measurement as a marker of transplantable leukemia in mice.
测定了可移植性白血病小鼠(P 388、L 1210标准型、L 1210/阿糖胞苷、L 1210/CH3-G、浆细胞瘤ADJPC-5、淋巴瘤AKSL-4以及NZB小鼠的自然白血病)血清中钴激活酰基转移酶的活性。结果表明,除淋巴细胞白血病外,所有白血病的酶活性均有统计学意义的升高。这些结果提示,酶活性测定有可能作为小鼠可移植性白血病的标志物。