[Glycoproteins and sialoproteins in the serum and internal organs of mice with transplantable leukemia].

Seromucoid and sialic acids in serum and histomucoid and sialic acids in internal organs were measured in BDF1, BALB/c and AKR 8 weeks old male mice with transplantable leukemia L1210, AKSL-4 and plasmocytoma ADJ PC-5. Statistically significant increase of seromucoid and sialic acids in serum was noted in both types of lymphatic leukemia. The level of both investigated parameters in internal organs also increased, except for the spleen where the decrease of both-histomucoid and sialic acids concentration was observed. In plasmocytoma ADJ PC-5 statistically significant decrease of seromucoid and histomucoid in spleen with simultaneous increase of sialic acids in serum and spleen were observed. Also, a significant increase of both parameters in liver and sialic acids in spleen was noticed.