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诊断核医学中 Tc-标记放射性药物的四肢暴露。

Extremity Exposure with Tc - Labelled Radiopharmaceuticals in Diagnostic Nuclear Medicine.

机构信息

Department of Medical Physics, School of Medicine, Sefako Makgatho Health Sciences University, Ga-Rankuwa, Pretoria, South Africa.

出版信息

Curr Radiopharm. 2021;14(1):57-63. doi: 10.2174/1874471013999200727205451.

DOI:10.2174/1874471013999200727205451
PMID:32720609
Abstract

BACKGROUND

Extremity exposures may raise the risk of cancer induction among radiographers involved in the preparation and administration of technetium-99m labelled radiopharmaceuticals.

OBJECTIVE

To estimate finger doses on radiographers at a South African tertiary hospital.

METHODS

Adhesive tape was used to securely fix a calibrated thermoluminescent dosimeter (TLD) on fingertips and bases of ring and index fingers of both hands of five radiographers who prepared and administered technetium-99m labelled radiopharmaceuticals. Rubber gloves were worn to avoid TLD contamination. TLDs doses were read with a Harsaw TLD Reader (Model 3500) after a week.

RESULTS

Five radiographers prepared and administered technitium-99m labelled radiopharmaceuticals (activity range; 78.20 GBq - 132.78 GBq during a one-week measurement period). A radiographer handling 132.78 GBq received 4.74±0.52 mSv on both hands; 5.52, 4.55, 5.11 and 4.60 mSv on the fingertip of the index finger of the dominant hand (FIDH), fingertip of the ring finger of the dominant hand (FRDH), fingertip of the index finger of the non-dominant hand (FINDH) and fingertip of the ring finger of the non-dominant hand (FRNDH), respectively. The respective doses received on the finger bases were 4.50 mSv, 4.60, 4.21 and 3.48 mSv. The radiographer handling 78.20 GBq received 0.85±0.18 mSv on both hands, 1.04, 1.17, 0.77 and 1 mSv for the FIDH, FRDH, FINDH and FRNDH, respectively, while respective doses for the bases were 0.8, 0.9, 0.6 and 0.8 mSv.

CONCLUSION

The extremity exposures were below the annual limit (500 mSv). However, the use of syringe shields could still reduce the finger doses further.

摘要

背景

在准备和管理锝-99m 标记放射性药物的过程中,放射技师的四肢暴露可能会增加癌症诱发的风险。

目的

估计南非一家三级医院放射技师的手指剂量。

方法

用粘性胶带将经过校准的热释光剂量计(TLD)固定在五名准备和管理锝-99m 标记放射性药物的放射技师的指尖和双手的环指和食指的底部。为了避免 TLD 污染,戴上橡胶手套。一周后,用 Harsaw TLD 读取器(型号 3500)读取 TLD 剂量。

结果

五名放射技师准备和管理锝-99m 标记放射性药物(一周测量期间的活动范围为 78.20GBq-132.78GBq)。一名处理 132.78GBq 的放射技师在双手上共接受 4.74±0.52mSv;优势手的食指指尖(FIDH)、优势手的环指指尖(FRDH)、非优势手的食指指尖(FINDH)和非优势手的环指指尖(FRNDH)的指尖分别为 5.52、4.55、5.11 和 4.60mSv;手指基底分别为 4.50mSv、4.60、4.21 和 3.48mSv。处理 78.20GBq 的放射技师在双手上共接受 0.85±0.18mSv;FIDH、FRDH、FINDH 和 FRNDH 的指尖分别为 1.04、1.17、0.77 和 1mSv;基底的相应剂量分别为 0.8、0.9、0.6 和 0.8mSv。

结论

四肢暴露量低于年限制(500mSv)。然而,使用注射器屏蔽器仍可进一步降低手指剂量。

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Curr Radiopharm. 2021;14(1):57-63. doi: 10.2174/1874471013999200727205451.
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