Kołodziej Artur, Ruman Tomasz, Nizioł Joanna
Doctoral School of Engineering and Technical Sciences, Rzeszów University of Technology, 8 Powstańców Warszawy Ave., Rzeszów, 35-959, Poland.
Faculty of Chemistry, Rzeszów University of Technology, 6 Powstańców Warszawy Ave., Rzeszów, 35-959, Poland.
J Mass Spectrom. 2020 Oct;55(10):e4604. doi: 10.1002/jms.4604.
A comparison of ionization efficiency for gold and silver nanoparticles used as an active media of matrix-less laser desorption/ionization (LDI) mass spectrometry (MS) methods was made for carboxylic acids including fatty acids. The matrix-assisted laser desorption/ionization (MALDI)-type targets containing monoisotopic cationic Ag nanoparticles ( AgNPs) and Au nanoparticles (AuNPs) were used for rapid MS measurements of 10 carboxylic acids of different chemical properties. Carboxylic acids were directly quantified in experiments with 10 000-fold concentration change conditions ranging from 1 mg/ml to 100 ng/ml which equates to 1 μg to 100 pg of carboxylic acids per measurement spot.
对用作无基质激光解吸/电离（LDI）质谱（MS）方法活性介质的金纳米颗粒和银纳米颗粒对包括脂肪酸在内的羧酸的电离效率进行了比较。含有单同位素阳离子银纳米颗粒（AgNPs）和金纳米颗粒（AuNPs）的基质辅助激光解吸/电离（MALDI）型靶材用于对10种化学性质不同的羧酸进行快速质谱测量。在浓度变化10000倍（范围从1mg/ml至100ng/ml，相当于每个测量点1μg至100pg羧酸）的条件下，通过实验对羧酸进行了直接定量。
