Universiti Sains Malaysia, School of Medical Sciences, Medicine Department, Kubang Kerian, Kelantan, Malaysia.
University of Malaya, Faculty of Medicine, Department of Primary Care Medicine, Kuala Lumpur, Malaysia.
Med J Malaysia. 2020 Jul;75(4):419-427.
Prediabetes, typically defined as blood glucose levels above normal but below diabetes thresholds, denotes a risk state that confers a high chance of developing diabetes. Asians, particularly the Southeast Asian population, may have a higher genetic predisposition to diabetes and increased exposure to environmental and social risk factors. Malaysia alone was home to 3.4 million people with diabetes in 2017; the figure is estimated to reach 6.1 million by 2045. Developing strategies for early interventions to treat prediabetes and preventing the development of overt diabetes and subsequent cardiovascular and microvascular complications are therefore important.
An expert panel comprising regional experts was convened in Kuala Lumpur, for a one-day meeting, to develop a document on prediabetes management in Malaysia. The expert panel comprised renowned subject-matter experts and specialists in diabetes and endocrinology, primary-care physicians, as well as academicians with relevant expertise.
Fifteen key clinical statements were proposed. The expert panel reached agreements on several important issues related to the management of prediabetes providing recommendations on the screening, diagnosis, lifestyle and pharmacological management of prediabetes. The expert panel also proposed changes in forthcoming clinical practice guidelines and suggested that the government should advocate early screening, detection, and intensive management of prediabetes.
This document provides a comprehensive approach to the management of prediabetes in Malaysia in their daily activities and offer help in improving government policies and the decision-making process.
糖尿病前期通常定义为血糖水平高于正常值但低于糖尿病阈值，表示处于一种高风险状态，很有可能发展为糖尿病。亚洲人，特别是东南亚人群，可能具有更高的糖尿病遗传易感性，并面临更多的环境和社会风险因素。仅马来西亚，2017 年就有 340 万人患有糖尿病；预计到 2045 年，这一数字将达到 610 万。因此，制定针对糖尿病前期的早期干预策略，预防显性糖尿病及其后续心血管和微血管并发症的发生，是非常重要的。
一个由区域专家组成的专家组在吉隆坡召开了为期一天的会议，制定了马来西亚糖尿病前期管理文件。专家组由著名的糖尿病和内分泌学领域的专家、初级保健医生以及具有相关专业知识的学者组成。
提出了 15 项关键临床陈述。专家组就与糖尿病前期管理相关的几个重要问题达成了一致意见，提供了糖尿病前期筛查、诊断、生活方式和药物管理的建议。专家组还建议对即将出台的临床实践指南进行修改，并建议政府倡导早期筛查、检测和强化糖尿病前期管理。
本文件为马来西亚日常活动中糖尿病前期的管理提供了一种全面的方法，并有助于改善政府政策和决策过程。
