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经口内镜下肌切开术的进展与挑战:安全性、精准性及术后管理

Advances and challenges in peroral endoscopic myotomy: Safety, precision, and post-procedure management.

作者信息

Christodoulidis Grigorios, Tsagkidou Kyriaki, Koumarelas Konstantinos Eleftherios, Kouliou Marina Nektaria

机构信息

Department of General Surgery, University Hospital of Larissa, Larissa 41110, Greece.

Department of Gastroenterology, General Hospital of Larissa, Larisa 41221, Thessalía, Greece.

出版信息

World J Gastroenterol. 2025 Feb 7;31(5):97574. doi: 10.3748/wjg.v31.i5.97574.

Abstract

Peroral endoscopic myotomy (POEM) has revolutionized the treatment of upper gastrointestinal tract motility disorders, particularly achalasia. This editorial explores the efficacy, safety, and challenges of POEM, emphasizing its role as a primary treatment with excellent long-term outcomes and minimal adverse events. The evolution of POEM underscores the need for precision in myotomy techniques and the importance of interdisciplinary collaboration, especially regarding anesthetic considerations. Despite significant advances, challenges remain in standardizing safety protocols and managing complications. As POEM applications expand, precision endoscopy continues to enhance therapeutic outcomes, promising a transformative impact on gastrointestinal motility disorder management.

摘要

经口内镜下肌切开术(POEM)彻底改变了上消化道动力障碍的治疗方式,尤其是贲门失弛缓症。这篇社论探讨了POEM的疗效、安全性和挑战,强调其作为主要治疗方法的作用,具有出色的长期效果且不良事件极少。POEM的发展凸显了肌切开术技术精确性的必要性以及跨学科合作的重要性,特别是在麻醉方面的考虑。尽管取得了重大进展,但在标准化安全协议和处理并发症方面仍存在挑战。随着POEM应用的扩展,精准内镜检查不断提高治疗效果,有望对胃肠动力障碍的管理产生变革性影响。

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