F-FDG PET/CT 检测结直肠癌淋巴结转移的准确性：系统评价和荟萃分析。
Is F-FDG PET/CT an Accurate Way to Detect Lymph Node Metastasis in Colorectal Cancer: A Systematic Review and Meta-Analysis.
机构信息
Department of Radiology, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran.
Students Research Committee, Zabol University of Medical Sciences, Zabol, Iran.
出版信息
Contrast Media Mol Imaging. 2020 Jul 18;2020:5439378. doi: 10.1155/2020/5439378. eCollection 2020.
AIMS
The purpose of this study was to assess the diagnostic value of F-fluorodeoxy-glucose positron emission tomography/computed tomography (FDG PET/CT) for detection of lymph node (LN) metastasis of colorectal cancer. . A computerized search was performed to determine the relevant articles, published before October 2019. Stata Statistical Software, version 15.0, and Meta-Disc (version 1.4) were used for the meta-analysis.
RESULTS
the sensitivity, specificity, positive likelihood ratio, and negative likelihood ratio were 0.65, 0.75, 4.57, and 0.37 respectively. Studies that used SUV cut-off value (≤2.5) demonstrated the best accuracy.
CONCLUSION
F-FDG PET/CT shows a low sensitivity and high specificity for detecting the metastasis of LNs in patients with newly diagnosed colorectal cancer.
目的
本研究旨在评估 F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG PET/CT）在检测结直肠癌淋巴结（LN）转移中的诊断价值。通过计算机检索，确定了 2019 年 10 月前发表的相关文章。使用 Stata 统计软件（版本 15.0）和 Meta-Disc（版本 1.4）进行荟萃分析。
结果
敏感性、特异性、阳性似然比和阴性似然比分别为 0.65、0.75、4.57 和 0.37。使用 SUV 截断值（≤2.5）的研究显示出最佳的准确性。
结论
对于诊断初诊结直肠癌患者的 LN 转移，FDG PET/CT 的敏感性较低，特异性较高。
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