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在印度,孕期和儿童期补充铁剂对 6-59 月龄儿童贫血的减少效果如何?

How Effective Is Iron Supplementation During Pregnancy and Childhood in Reducing Anemia Among 6-59 Months Old Children in India?

机构信息

Gerald and Patricia Turpanjian School of Public Health, American University of Armenia, Yerevan, Armenia.

出版信息

Front Public Health. 2020 Jul 7;8:234. doi: 10.3389/fpubh.2020.00234. eCollection 2020.

DOI:10.3389/fpubh.2020.00234
PMID:32733832
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7359635/
Abstract

The study sought to identify whether iron and folic acid supplementation of pregnant women and preschool children is associated with child's anemia status and the predictors of anemia among children in India. Secondary data analysis was performed using the National Family Health Survey 4 data. Multivariable logistic regression was used to identify the adjusted associations between child's anemia status and iron supplementation, both during pregnancy and childhood. Also, a model of significant predictors of anemia among children was fitted. India. Youngest children (6-59 months) in families. The adjusted association between supplementation during pregnancy and child's anemia status was significant ( = 0.010), whereas the adjusted association between supplementation during childhood and child's anemia status was insignificant ( = 0.16). The variables independently associated with anemia status of the child included younger age (95% CI 2.67-2.86), child's recent diarrhea (95% CI 1.02-1.14), low birth weight (95% CI 1.17-1.27), current underweight (95% CI 1.14-1.28), diet diversity score (95% CI 0.96-0.98), higher birth order (95% CI 1.01-1.05), mother's current anemia (95% CI 1.68-1.81), months of breastfeeding (95% CI 0.99-1.00), no/primary education (95% CI 1.23-1.35), family's low wealth index (95% CI 1.11-1.23), and backward caste (95% CI 1.04-1.14). The National Iron Plus Initiative strategy of child's iron supplementation should be evaluated to identify the reasons of its ineffectiveness in anemia reduction. In addition, vulnerable groups of children, i.e., children from poor and less educated families and those with low birth weight, higher birth order, and poor nutritional status, should be targeted first with anemia reduction interventions.

摘要

本研究旨在探讨孕妇和学龄前儿童补充铁和叶酸是否与儿童贫血状况有关,并确定印度儿童贫血的预测因素。使用国家家庭健康调查 4 数据进行二次数据分析。采用多变量逻辑回归来确定儿童贫血状况与铁补充之间的调整关联,包括怀孕期间和儿童时期的补充。还拟合了儿童贫血的显著预测因素模型。

印度。家庭中年龄最小的儿童(6-59 个月)。怀孕期间补充与儿童贫血状况之间的调整关联具有统计学意义(=0.010),而儿童时期补充与儿童贫血状况之间的调整关联无统计学意义(=0.16)。与儿童贫血状况独立相关的变量包括年龄较小(95%CI 2.67-2.86)、儿童近期腹泻(95%CI 1.02-1.14)、低出生体重(95%CI 1.17-1.27)、当前体重不足(95%CI 1.14-1.28)、饮食多样性评分(95%CI 0.96-0.98)、较高的出生顺序(95%CI 1.01-1.05)、母亲当前贫血(95%CI 1.68-1.81)、母乳喂养月数(95%CI 0.99-1.00)、无/小学教育(95%CI 1.23-1.35)、家庭低财富指数(95%CI 1.11-1.23)和落后种姓(95%CI 1.04-1.14)。应评估儿童铁补充的国家铁加计划战略,以确定其在减少贫血方面无效的原因。此外,应首先针对来自贫困和受教育程度较低家庭以及出生体重低、出生顺序高和营养状况差的儿童等弱势群体开展减少贫血的干预措施。

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