Norton Pedro, Araújo Natália, Pinho Paulo, Costa Gomes Joana, Silva Carla, Gama Céline, Barbosa Manuel, Ferreira Pedro, Cunha Sara, Moreira Sara, Martins Sílvia, Faria Sofia, Sousa Sophie, Figueiras Alves Nuno, Lunet Nuno
Occupational Health Service, S. João Hospital Center.
EPIUnit - Publick Health Institut, University of Porto, Rua das Taipas.
Porto Biomed J. 2020 Jul 17;5(4):e064. doi: 10.1097/j.pbj.0000000000000064. eCollection 2020 Jul-Aug.
Little is known about iron deficiency anemia (IDA)'s treatment in Portugal. We aim to estimate the proportion of anemia, IDA, and iron deficiency without anemia; characterize the diagnostic procedures and prescription patterns; assess anemia's impact over work absenteeism, in a Local Health Unit.
Cross-sectional study that evaluated complete blood counts, iron-containing prescriptions, comorbidities, economic failure, and disability certificates issued in 2015 at the Local Health Unit.
We evaluated 62,794 complete blood count. The proportion of anemia was 16.5%, higher in patients with economic failure, pregnant women, and patients with congestive heart failure. Of the patients with anemia 87.8% had not serum iron and/or ferritin dosing, and of those with serum iron/ferritin levels tested 50.6% had IDA. IDA was higher in pregnant women, women aged ≥15 years and in patients with congestive heart failure. Approximately 56.2% of patients with IDA did not receive iron-containing medication, and in 38% of the cases the prescribed dose was subtherapeutic. Of the total iron prescriptions 44.1% were association therapies. Anemia accounted for 5.2% of the disability certificates issued in 2015 (1749 workdays lost).
Most patients with anemia are not being adequately evaluated and a major proportion does not undergo treatment or has subtherapeutic doses of iron. These results may explain the anemia's impact on work capacity.
This is one of the largest studies on anemia in Portugal. An effort to adapt to the established recommendations is urged, to minimize the consequences of this disease.
在葡萄牙，关于缺铁性贫血（IDA）的治疗鲜为人知。我们旨在估计贫血、IDA和缺铁但无贫血的比例；描述诊断程序和处方模式；评估在一个地方卫生单位中贫血对旷工的影响。
横断面研究，评估了2015年在该地方卫生单位开具的全血细胞计数、含铁处方、合并症、经济困难情况及残疾证明。
我们评估了62794份全血细胞计数。贫血比例为16.5%，在经济困难患者、孕妇和充血性心力衰竭患者中更高。在贫血患者中，87.8%未进行血清铁和/或铁蛋白检测，而在进行了血清铁/铁蛋白水平检测的患者中，50.6%患有IDA。孕妇、年龄≥15岁的女性和充血性心力衰竭患者中的IDA比例更高。约56.2%的IDA患者未接受含铁药物治疗，在38%的病例中，规定剂量低于治疗剂量。在所有铁剂处方中，44.1%为联合治疗。贫血占2015年所发放残疾证明的5.2%（损失1749个工作日）。
大多数贫血患者未得到充分评估，很大一部分患者未接受治疗或铁剂剂量低于治疗剂量。这些结果可能解释了贫血对工作能力的影响。
这是葡萄牙关于贫血的最大规模研究之一。敦促努力遵循既定建议，以尽量减少这种疾病的后果。
