Center for Cancer and Blood Disorders, Phoenix Children's Hospital, 1919 E. Thomas Road, Phoenix, AZ, 85021, USA.
Department of Pharmacy, Phoenix Children's Hospital, 1919 E. Thomas Road, Phoenix, AZ, 85021, USA.
Support Care Cancer. 2021 Mar;29(3):1549-1555. doi: 10.1007/s00520-020-05652-1. Epub 2020 Jul 30.
Two of the most common acute side effects of chemotherapy are nausea and vomiting. Nausea and vomiting impact quality of life, nutritional status, and ability to tolerate further chemotherapy. Parents of pediatric oncology patients rank nausea as one of the most bothersome treatment-related symptoms.
Utilizing Quality Improvement methodology, we developed a dashboard interface to facilitate extraction of data from the electronic medical record (EMR), which is presented via a visual display that summarizes the type of chemotherapy and antiemetic medications, use of as needed medications, and number of episodes of emesis.
This dashboard interface allows for rapid and efficient identification of patients whose antiemetic regimen is mismatched for the emetogenicity of ordered chemotherapy, thus providing a timely opportunity to modify the antiemetic regimen based on published guidelines before administration of chemotherapy drugs. It also allows measurement of the effectiveness of the antiemetic regimen in terms of the number of break through emesis and the need for as needed medications.
A novel CINV dashboard was created, which visually conveys complex information about antiemetics, chemotherapy emetogenicity, as needed medications, and breakthrough vomiting for inpatient pediatric oncology patients.
化疗最常见的两种急性副作用是恶心和呕吐。恶心和呕吐会影响生活质量、营养状况和耐受进一步化疗的能力。儿科肿瘤患者的家长将恶心列为最令人困扰的治疗相关症状之一。
利用质量改进方法，我们开发了一个仪表板界面，以方便从电子病历（EMR）中提取数据，该界面通过可视化显示进行呈现，总结了化疗类型和止吐药物、按需使用药物的情况以及呕吐发作的次数。
该仪表板界面可快速有效地识别出止吐方案与所开化疗药物致吐性不匹配的患者，从而有机会在给予化疗药物之前根据已发布的指南及时修改止吐方案。它还可以衡量止吐方案在突破性呕吐次数和按需用药需求方面的有效性。
创建了一种新颖的 CINV 仪表板，直观地传达了有关止吐药、化疗致吐性、按需用药和住院儿科肿瘤患者突破性呕吐的复杂信息。
