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根治性肾切除术后17年透明细胞肾细胞癌转移至坐骨直肠窝的首例报告:终身随访的另一个原因

First report of clear cell renal carcinoma metastasizing to the ischiorectal fossa 17 years after radical nephrectomy: an additional reason for lifelong follow-up.

作者信息

Zygomalas A, Papachristou D J, Katsiakis N, Karatzas A, Kourelis T, Georgostathis K, Karavias D

机构信息

Olympion General Clinic, Patras, Greece.

出版信息

Ann R Coll Surg Engl. 2020 Nov;102(9):e1-e3. doi: 10.1308/rcsann.2020.0140. Epub 2020 Jul 31.

DOI:10.1308/rcsann.2020.0140
PMID:32734776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7591596/
Abstract

Renal cell carcinoma has a high propensity for metastatic spread. There are several case reports of metastatic renal cell carcinomas associated with rare metastatic sites, in many cases more than ten years after the initial diagnosis. We present a 60-year-old man with perianal pain and a mass in the ischiorectal space, revealed by computed tomography. The patient had a history of clear cell renal carcinoma operated on 17 years ago. A wire localization surgical excision of the ischiorectal fossa mass was performed. The pathological report revealed a metastatic clear cell renal carcinoma. To our knowledge, this is the first case of a clear cell renal carcinoma metastasizing to the ischiorectal fossa reported in the literature. We therefore recommend that any newly discovered mass in any site of a patient with a history of renal cell carcinoma should be carefully explored and biopsied.

摘要

肾细胞癌具有较高的转移扩散倾向。有几例关于转移性肾细胞癌与罕见转移部位相关的病例报告,在许多情况下,是在初次诊断十多年后出现。我们报告一名60岁男性,因肛周疼痛和坐骨直肠窝肿物就诊,计算机断层扫描显示了该肿物。该患者17年前曾接受过透明细胞肾细胞癌手术。对坐骨直肠窝肿物进行了金属丝定位手术切除。病理报告显示为转移性透明细胞肾细胞癌。据我们所知,这是文献中报道的首例透明细胞肾细胞癌转移至坐骨直肠窝的病例。因此,我们建议,对于有肾细胞癌病史的患者,其任何部位新发现的肿物都应进行仔细探查和活检。

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1
First report of clear cell renal carcinoma metastasizing to the ischiorectal fossa 17 years after radical nephrectomy: an additional reason for lifelong follow-up.根治性肾切除术后17年透明细胞肾细胞癌转移至坐骨直肠窝的首例报告:终身随访的另一个原因
Ann R Coll Surg Engl. 2020 Nov;102(9):e1-e3. doi: 10.1308/rcsann.2020.0140. Epub 2020 Jul 31.
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本文引用的文献

1
Atypical presentations and rare metastatic sites of renal cell carcinoma: a review of case reports.肾细胞癌的非典型表现及罕见转移部位:病例报告综述
J Med Case Rep. 2011 Sep 2;5:429. doi: 10.1186/1752-1947-5-429.
2
Imaging of unusual perineal masses.会阴部罕见肿块的影像学表现。
AJR Am J Roentgenol. 2011 Apr;196(4):W412-20. doi: 10.2214/AJR.10.4728.
3
Recurrent renal cell cancer: 10 years or more after nephrectomy.复发性肾细胞癌:肾切除术后10年或更长时间。
Can Urol Assoc J. 2010 Apr;4(2):E45-9. doi: 10.5489/cuaj.829.
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The normal and pathologic ischiorectal fossa at CT and MR imaging.
Radiographics. 1998 Jan-Feb;18(1):61-82; quiz 146. doi: 10.1148/radiographics.18.1.9460109.