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[一名53岁新冠肺炎男性患者的尸检CT及尸检结果]

[Findings in post-mortem CT and autopsy in a 53-year-old-man with COVID-19].

作者信息

Leth Peter Mygind, Rasmussen Claus-Henrik, Pagh Mette

出版信息

Ugeskr Laeger. 2020 Jul 6;182(28).

PMID:32734876
Abstract

In this case report, a 53-year old man died after ten days with fever and coughing and was tested positive for coronavirus disease 2019 (COVID-19). A post-mortem CT disclosed ground-glass opacities with focal consolidation in both lungs. At autopsy, the lungs were dark and heavy with increased consistency and without pleural fibrin. Microscopy of lung tissue showed diffuse alveolar damage with hyaline membranes, sparse chronic interstitial inflammation and foci of bronchopneumonia. The deceased was a non-smoker, who did not suffer from a serious illness. He was overweight (BMI = 34 kg/m2), an emerging predictor for poor outcome of COVID-19.

摘要

在本病例报告中,一名53岁男性在出现发热和咳嗽十天后死亡,新型冠状病毒肺炎(COVID-19)检测呈阳性。尸检CT显示双肺磨玻璃影伴局灶性实变。尸检时,肺脏颜色灰暗、重量增加、质地变硬且无胸膜纤维蛋白。肺组织显微镜检查显示弥漫性肺泡损伤伴透明膜形成、稀疏的慢性间质性炎症和支气管肺炎病灶。死者不吸烟,无严重疾病史。他超重(体重指数=34kg/m²),这是COVID-19预后不良的一个新的预测因素。

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引用本文的文献

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Postmortem Chest Computed Tomography in Fatal COVID-19: A Valuable Diagnostic Tool for Minimally Invasive Autopsy.致命性新冠肺炎的尸检胸部计算机断层扫描:一种用于微创尸检的有价值诊断工具。
Clinics (Sao Paulo). 2021 Dec 8;76:e3551. doi: 10.6061/clinics/2021/e3551. eCollection 2021.
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Autopsy Tool in Unknown Diseases: The Experience with Coronaviruses (SARS-CoV, MERS-CoV, SARS-CoV-2).不明疾病尸检工具:冠状病毒(SARS-CoV、MERS-CoV、SARS-CoV-2)经验。
Medicina (Kaunas). 2021 Mar 25;57(4):309. doi: 10.3390/medicina57040309.
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COVID-19 lungs in post-mortem computed tomography.
新冠病毒肺炎患者尸体解剖计算机断层扫描结果
Rechtsmedizin (Berl). 2021;31(2):145-147. doi: 10.1007/s00194-021-00462-z. Epub 2021 Feb 15.