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新冠病毒肺炎患者尸体解剖计算机断层扫描结果

COVID-19 lungs in post-mortem computed tomography.

作者信息

Kniep I, Heinemann A, Edler C, Sperhake J P, Püschel K, Ondruschka B, Schröder A S

机构信息

Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529 Hamburg, Germany.

出版信息

Rechtsmedizin (Berl). 2021;31(2):145-147. doi: 10.1007/s00194-021-00462-z. Epub 2021 Feb 15.

Abstract

Post-mortem computed tomography (PMCT) is a rapid and noninvasive diagnostic tool for important contributions to the identification of pulmonary findings in the deceased with pneumonia, including cases of coronavirus disease 2019 (COVID-19). Although computed tomography (CT) shows a high sensitivity for pneumonia in living persons, it is relatively unspecific for COVID-19 pneumonia clinically. Typical CT findings for viral pneumonia therefore require confirmation by PCR tests (polymerase chain reaction tests), even if lung infections with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) show characteristic patterns, most frequently ground glass opacities (GGO) and a combination of GGO and air space consolidations. In the consecutive autopsy series of SARS-CoV‑2 deaths from Hamburg, Germany, the most frequent cause of death was and still is COVID-19 pneumonia. Typical findings were frequently found in the PMCT in SARS-CoV-2-associated deaths, which were taken into account when classifying the death as COVID-19.

摘要

尸检计算机断层扫描(PMCT)是一种快速且无创的诊断工具,对识别肺炎死者的肺部发现有重要作用,包括2019冠状病毒病(COVID-19)病例。尽管计算机断层扫描(CT)对活人肺炎显示出高敏感性,但在临床上对COVID-19肺炎相对缺乏特异性。因此,病毒性肺炎的典型CT表现需要通过PCR检测(聚合酶链反应检测)来确认,即使严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的肺部感染呈现出特征性模式,最常见的是磨玻璃影(GGO)以及GGO与实变影的组合。在德国汉堡连续的SARS-CoV-2死亡病例尸检系列中,最常见的死亡原因过去是、现在仍然是COVID-19肺炎。在SARS-CoV-2相关死亡病例的PMCT中经常发现典型表现,在将死亡归类为COVID-19时会考虑这些表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/320c44f38952/194_2021_462_Fig1_HTML.jpg

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