• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

新冠病毒肺炎患者尸体解剖计算机断层扫描结果

COVID-19 lungs in post-mortem computed tomography.

作者信息

Kniep I, Heinemann A, Edler C, Sperhake J P, Püschel K, Ondruschka B, Schröder A S

机构信息

Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Butenfeld 34, 22529 Hamburg, Germany.

出版信息

Rechtsmedizin (Berl). 2021;31(2):145-147. doi: 10.1007/s00194-021-00462-z. Epub 2021 Feb 15.

DOI:10.1007/s00194-021-00462-z
PMID:33612977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7884063/
Abstract

Post-mortem computed tomography (PMCT) is a rapid and noninvasive diagnostic tool for important contributions to the identification of pulmonary findings in the deceased with pneumonia, including cases of coronavirus disease 2019 (COVID-19). Although computed tomography (CT) shows a high sensitivity for pneumonia in living persons, it is relatively unspecific for COVID-19 pneumonia clinically. Typical CT findings for viral pneumonia therefore require confirmation by PCR tests (polymerase chain reaction tests), even if lung infections with severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) show characteristic patterns, most frequently ground glass opacities (GGO) and a combination of GGO and air space consolidations. In the consecutive autopsy series of SARS-CoV‑2 deaths from Hamburg, Germany, the most frequent cause of death was and still is COVID-19 pneumonia. Typical findings were frequently found in the PMCT in SARS-CoV-2-associated deaths, which were taken into account when classifying the death as COVID-19.

摘要

尸检计算机断层扫描(PMCT)是一种快速且无创的诊断工具,对识别肺炎死者的肺部发现有重要作用,包括2019冠状病毒病(COVID-19)病例。尽管计算机断层扫描(CT)对活人肺炎显示出高敏感性,但在临床上对COVID-19肺炎相对缺乏特异性。因此,病毒性肺炎的典型CT表现需要通过PCR检测(聚合酶链反应检测)来确认,即使严重急性呼吸综合征冠状病毒2型(SARS-CoV-2)引起的肺部感染呈现出特征性模式,最常见的是磨玻璃影(GGO)以及GGO与实变影的组合。在德国汉堡连续的SARS-CoV-2死亡病例尸检系列中,最常见的死亡原因过去是、现在仍然是COVID-19肺炎。在SARS-CoV-2相关死亡病例的PMCT中经常发现典型表现,在将死亡归类为COVID-19时会考虑这些表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/992ad0afdbbb/194_2021_462_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/320c44f38952/194_2021_462_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/c38b9309ac15/194_2021_462_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/992ad0afdbbb/194_2021_462_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/320c44f38952/194_2021_462_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/c38b9309ac15/194_2021_462_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a668/7884063/992ad0afdbbb/194_2021_462_Fig3_HTML.jpg

相似文献

1
COVID-19 lungs in post-mortem computed tomography.新冠病毒肺炎患者尸体解剖计算机断层扫描结果
Rechtsmedizin (Berl). 2021;31(2):145-147. doi: 10.1007/s00194-021-00462-z. Epub 2021 Feb 15.
2
Postmortem CT pulmonary findings in SARS-CoV-2-positive cases: correlation with lung histopathological findings and autopsy results.COVID-19 逝者的 CT 肺部影像表现:与肺组织病理发现及尸检结果的相关性。
Int J Legal Med. 2022 Sep;136(5):1407-1415. doi: 10.1007/s00414-022-02793-2. Epub 2022 Feb 14.
3
Use of post-mortem chest computed tomography in Covid-19 pneumonia.死后胸部计算机断层扫描在新冠肺炎肺炎中的应用。
Forensic Sci Int. 2021 Aug;325:110851. doi: 10.1016/j.forsciint.2021.110851. Epub 2021 May 27.
4
Post-mortem CT lung findings at a medicolegal institute in SARS-CoV-2 RT-PCR positive cases with autopsy correlation.SARS-CoV-2 RT-PCR 阳性病例尸检相关性分析:法医学研究所中死后 CT 肺部检查结果。
Forensic Sci Med Pathol. 2021 Dec;17(4):611-620. doi: 10.1007/s12024-021-00389-7. Epub 2021 Jun 23.
5
Potentials of post-mortem CT investigations during SARS-COV-2 pandemic: a narrative review.SARS-CoV-2 大流行期间尸检 CT 研究的潜力:叙述性综述。
Radiol Med. 2022 Apr;127(4):383-390. doi: 10.1007/s11547-022-01457-w. Epub 2022 Feb 28.
6
Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations.COVID-19 致死病例的完整尸检数据:临床、影像学和病理学相关性。
Int J Legal Med. 2020 Nov;134(6):2209-2214. doi: 10.1007/s00414-020-02390-1. Epub 2020 Aug 6.
7
Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany.死于 SARS-CoV-2 感染——德国汉堡首例连续 80 例尸检研究。
Int J Legal Med. 2020 Jul;134(4):1275-1284. doi: 10.1007/s00414-020-02317-w. Epub 2020 Jun 4.
8
Atypical Chest Computed Tomography Finding of Predominant Interstitial Thickening in a Patient with Coronavirus Disease 2019 (COVID-19) Pneumonia.一名2019冠状病毒病(COVID-19)肺炎患者胸部计算机断层扫描的非典型表现:以间质增厚为主
Am J Case Rep. 2020 Sep 21;21:e926781. doi: 10.12659/AJCR.926781.
9
Post-mortem computed tomography findings of the lungs: Retrospective review and comparison with autopsy results of 30 infant cases.肺部的尸检计算机断层扫描结果:30例婴儿病例的回顾性分析及与尸检结果的比较
Eur J Radiol. 2015 Apr;84(4):721-5. doi: 10.1016/j.ejrad.2014.12.002. Epub 2014 Dec 24.
10
Imaging and clinical features of patients with 2019 novel coronavirus SARS-CoV-2.新型冠状病毒 2019 年 SARS-CoV-2 患者的影像学和临床特征。
Eur J Nucl Med Mol Imaging. 2020 May;47(5):1275-1280. doi: 10.1007/s00259-020-04735-9. Epub 2020 Feb 28.

引用本文的文献

1
Technologies for Studying and Teaching Human Anatomy: Implications in Academic Education.人体解剖学学习与教学技术:对学术教育的启示
Med Sci Educ. 2024 May 28;34(5):1203-1214. doi: 10.1007/s40670-024-02079-9. eCollection 2024 Oct.
2
Minimally Invasive Tissue Sampling via Post Mortem Ultrasound: A Feasible Tool (Not Only) in Infectious Diseases-A Case Report.通过尸检超声进行微创组织采样:一种(不仅)在传染病中可行的工具——病例报告
Diagnostics (Basel). 2023 Aug 10;13(16):2643. doi: 10.3390/diagnostics13162643.
3
Postmortem CT in decedents with SARS-CoV-2 infection. A single institution experience.

本文引用的文献

1
Evidence for systematic autopsies in COVID-19 positive deceased: Case report of the first German investigated COVID-19 death.COVID-19阳性死者进行系统尸检的证据:首例德国调查的COVID-19死亡病例报告。
Rechtsmedizin (Berl). 2020;30(3):184-189. doi: 10.1007/s00194-020-00401-4. Epub 2020 May 25.
2
[Postmortem imaging of the lung in cases of COVID-19 deaths].[新型冠状病毒肺炎死亡病例的肺部尸检影像学]
Radiologe. 2020 Oct;60(10):927-933. doi: 10.1007/s00117-020-00733-y.
3
Complete post-mortem data in a fatal case of COVID-19: clinical, radiological and pathological correlations.
SARS-CoV-2感染死者的尸检CT。单机构经验。
Forensic Sci Res. 2022 Jan 24;7(2):255-260. doi: 10.1080/20961790.2021.1977479. eCollection 2022.
4
Organ manifestations of COVID-19: what have we learned so far (not only) from autopsies?COVID-19 的器官表现:迄今为止(不仅)从尸检中学到了什么?
Virchows Arch. 2022 Aug;481(2):139-159. doi: 10.1007/s00428-022-03319-2. Epub 2022 Apr 1.
5
Postmortem Chest Computed Tomography in Fatal COVID-19: A Valuable Diagnostic Tool for Minimally Invasive Autopsy.致命性新冠肺炎的尸检胸部计算机断层扫描:一种用于微创尸检的有价值诊断工具。
Clinics (Sao Paulo). 2021 Dec 8;76:e3551. doi: 10.6061/clinics/2021/e3551. eCollection 2021.
6
Molecular docking of SARS-COV-2 Spike epitope sequences identifies heterodimeric peptide-protein complex formation with human Zo-1, TLR8 and brain specific glial proteins.SARS-COV-2 刺突表位序列的分子对接鉴定出人 Zo-1、TLR8 和脑特异性神经胶质蛋白的异二聚体肽-蛋白复合物形成。
Med Hypotheses. 2021 Dec;157:110706. doi: 10.1016/j.mehy.2021.110706. Epub 2021 Oct 13.
7
Use of post-mortem chest computed tomography in Covid-19 pneumonia.死后胸部计算机断层扫描在新冠肺炎肺炎中的应用。
Forensic Sci Int. 2021 Aug;325:110851. doi: 10.1016/j.forsciint.2021.110851. Epub 2021 May 27.
COVID-19 致死病例的完整尸检数据:临床、影像学和病理学相关性。
Int J Legal Med. 2020 Nov;134(6):2209-2214. doi: 10.1007/s00414-020-02390-1. Epub 2020 Aug 6.
4
[Findings in post-mortem CT and autopsy in a 53-year-old-man with COVID-19].[一名53岁新冠肺炎男性患者的尸检CT及尸检结果]
Ugeskr Laeger. 2020 Jul 6;182(28).
5
Clinical and radiological features of novel coronavirus pneumonia.新型冠状病毒肺炎的临床和影像学特征。
J Xray Sci Technol. 2020;28(3):391-404. doi: 10.3233/XST-200687.
6
Chest CT features of coronavirus disease 2019 (COVID-19) pneumonia: key points for radiologists.COVID-19 肺炎的胸部 CT 特征:放射科医生的关键点。
Radiol Med. 2020 Jul;125(7):636-646. doi: 10.1007/s11547-020-01237-4. Epub 2020 Jun 4.
7
Dying with SARS-CoV-2 infection-an autopsy study of the first consecutive 80 cases in Hamburg, Germany.死于 SARS-CoV-2 感染——德国汉堡首例连续 80 例尸检研究。
Int J Legal Med. 2020 Jul;134(4):1275-1284. doi: 10.1007/s00414-020-02317-w. Epub 2020 Jun 4.
8
Autopsy Findings and Venous Thromboembolism in Patients With COVID-19: A Prospective Cohort Study.COVID-19 患者的尸检结果与静脉血栓栓塞:一项前瞻性队列研究。
Ann Intern Med. 2020 Aug 18;173(4):268-277. doi: 10.7326/M20-2003. Epub 2020 May 6.
9
Postmortem examination of COVID-19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction.对新冠病毒疾病(COVID-19)患者的尸检显示,肺部出现弥漫性肺泡损伤,伴有严重的毛细血管充血,肺部及其他器官呈现出多样化的表现,提示存在血管功能障碍。
Histopathology. 2020 Aug;77(2):198-209. doi: 10.1111/his.14134. Epub 2020 Jul 5.
10
Chest CT manifestations of new coronavirus disease 2019 (COVID-19): a pictorial review.新型冠状病毒病 2019(COVID-19)的胸部 CT 表现:影像学综述。
Eur Radiol. 2020 Aug;30(8):4381-4389. doi: 10.1007/s00330-020-06801-0. Epub 2020 Mar 19.