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胆囊严重积脓的罕见表现:病例报告及文献复习。

Uncommon Presentation of Severe Empyema of the Gallbladder: Case Report and Literature Review.

机构信息

Department of Surgery, Kendall Regional Medical Center, Miami, FL, USA.

Department of Surgery, University of South Florida, Tampa, FL, USA.

出版信息

Am J Case Rep. 2020 Jul 31;21:e923040. doi: 10.12659/AJCR.923040.

DOI:10.12659/AJCR.923040
PMID:32734934
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7414827/
Abstract

BACKGROUND Empyema of the gallbladder is a complication of cholecystitis that can develop into sepsis if not treated promptly. Signs and symptoms of gallstone disease are nausea/vomiting, right upper quadrant tenderness, and a history of gallstone disease. With persistence of the obstruction, inflammation and bacterial overgrowth within the gallbladder lumen and tissue may lead to eventual venous congestion, pressure necrosis and even empyema of the gallbladder. CASE REPORT A 60-year old male presented with complaints of mild mid-epigastric pain radiating to the back. He denied previous similar history. CT and ultrasound of the abdomen revealed acute cholecystitis. During surgery, it was clear that the imaging did not accurately represent the severity of the infection and he was diagnosed with gallbladder empyema. Surgery was difficult but was successfully finished. The patient's symptoms and laboratory results normalized by post-operative day 3 and he was discharged. He had no further complications during 2-week follow up. CONCLUSIONS Physicians should keep the abnormal presentations of gallbladder empyema in mind and prepare themselves for a presentation different from imaging during surgery. Several prognostic factors including gallbladder wall thickness, gender, white cell count and diabetes mellitus have been associated with severe complicated cholecystitis and empyema of the gallbladder.

摘要

背景

胆囊积脓是胆囊炎的一种并发症,如果不及时治疗,可能会发展为败血症。胆石病的症状和体征包括恶心/呕吐、右上腹压痛和胆石病病史。随着梗阻的持续存在,胆囊腔内和组织中的炎症和细菌过度生长可能导致最终静脉充血、压迫性坏死,甚至胆囊积脓。

病例报告

一名 60 岁男性因轻度中上腹痛放射至背部就诊。他否认有类似的既往病史。腹部 CT 和超声显示急性胆囊炎。术中发现影像学检查不能准确反映感染的严重程度,诊断为胆囊积脓。手术难度较大,但最终成功完成。术后第 3 天,患者症状和实验室结果恢复正常并出院。在 2 周的随访中,他没有出现进一步的并发症。

结论

医生应牢记胆囊积脓的异常表现,并为术中不同于影像学的表现做好准备。一些预后因素,包括胆囊壁厚度、性别、白细胞计数和糖尿病,与严重的复杂胆囊炎和胆囊积脓有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03b9/7414827/148793589748/amjcaserep-21-e923040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03b9/7414827/148793589748/amjcaserep-21-e923040-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/03b9/7414827/148793589748/amjcaserep-21-e923040-g003.jpg

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Ann Hepatobiliary Pancreat Surg. 2019 Aug;23(3):228-233. doi: 10.14701/ahbps.2019.23.3.228. Epub 2019 Aug 30.
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Prognostic Value of Preoperative Neutrophil-to-lymphocyte Ratio for Prediction of Severe Cholecystitis.术前中性粒细胞与淋巴细胞比值对预测重症胆囊炎的预后价值
J Med Biochem. 2018 Apr 1;37(2):121-127. doi: 10.1515/jomb-2017-0063. eCollection 2018 Apr.
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The outcome of laparoscopic subtotal cholecystectomy in difficult cases - A case series.
困难病例行腹腔镜胆囊次全切除术的结果——病例系列报道
Int J Surg Case Rep. 2017;41:311-314. doi: 10.1016/j.ijscr.2017.10.054. Epub 2017 Nov 8.
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The SCARE Statement: Consensus-based surgical case report guidelines.SCARE 声明:基于共识的外科手术病例报告指南。
Int J Surg. 2016 Oct;34:180-186. doi: 10.1016/j.ijsu.2016.08.014. Epub 2016 Sep 7.
5
Laparoscopic modified subtotal cholecystectomy for difficult gall bladders: A single-centre experience.腹腔镜改良胆囊次全切除术治疗复杂胆囊:单中心经验
J Minim Access Surg. 2016 Oct-Dec;12(4):325-9. doi: 10.4103/0972-9941.181323.
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Gallbladder Empyema.胆囊积脓
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Surgical management of empyematous cholecystitis: a register study of over 12,000 cases from a regional quality control database in Germany.脓性胆囊炎的外科治疗:一项来自德国地区质量控制数据库的超过12000例病例的登记研究。
Surg Endosc. 2016 Dec;30(12):5319-5324. doi: 10.1007/s00464-016-4882-1. Epub 2016 May 13.
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Subtotal cholecystectomy for "difficult gallbladders": systematic review and meta-analysis.“困难胆囊”行次全胆囊切除术:系统评价和荟萃分析。
JAMA Surg. 2015 Feb;150(2):159-68. doi: 10.1001/jamasurg.2014.1219.
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