Cicioğlu R, Payzin S, Yakar A
Ankara Universitesi, Tip Fakültesi, Mikrobiyoloji Anabilim Dali.
Mikrobiyol Bul. 1988 Apr;22(2):142-63.
Immediate and delayed skin reactions against ten group of allergens were investigated in 355 patients with urticaria and angioneurotic edema. The wheal and flare reaction were characteristic of the type I-IgE mediated hypersensitivity reaction in human skin. This reaction develops rapidly after injection of antigen, peaking 10-30 minutes, and then subsides within a few hours. However, careful observation for longer periods, has shown that in many instances a late inflammatory response also appears at the same site and is quite different in appearance from the initial reaction. In this study, we have investigated in immediate and also delayed-phase skin reactivity, incidence of the patients.
对355例荨麻疹和血管神经性水肿患者针对十组变应原进行了速发和迟发性皮肤反应的研究。风团和潮红反应是人类皮肤中I型IgE介导的超敏反应的特征。这种反应在注射抗原后迅速出现，10 - 30分钟达到峰值，然后在数小时内消退。然而，长时间的仔细观察表明，在许多情况下，同一部位也会出现晚期炎症反应，其外观与初始反应有很大不同。在本研究中，我们调查了患者的速发和迟发期皮肤反应性及发生率。
