Tsicopoulos A, Fahy O, Tonnel A B
INSERM U. 416, Institut Pasteur de Lille, and Service de Pneumo-Immuno-Allergologie, Hôpital Calmette, Lille, France.
Eur J Dermatol. 1999 Jun;9(4):261-8.
Tuberculin-induced delayed type hypersensitivity and allergen-induced late phase responses are two types of cutaneous inflammatory reactions mediated by antigen-specific T cells and involving distinct pathophysiological mechanisms. In humans, different types of cellular infiltration as well as cytokine profiles have been ascribed to each reaction. A more precise analysis of these reactions shows that in fact they are complementary, intricated, and cross regulatory, and that they represent interesting models to evaluate the regulation of some pathological disorders.
结核菌素诱导的迟发型超敏反应和变应原诱导的迟发相反应是由抗原特异性T细胞介导的两种皮肤炎症反应，涉及不同的病理生理机制。在人类中，每种反应都有不同类型的细胞浸润以及细胞因子谱。对这些反应进行更精确的分析表明，事实上它们是互补的、错综复杂的且相互调节的，并且它们代表了评估某些病理疾病调节的有趣模型。
