Department of Neurology, Wake Forest Baptist Medical Center, Winston-Salem, NC, United States.
Department of Neurology, Wake Forest Baptist Medical Center, Winston-Salem, NC, United States.
Handb Clin Neurol. 2020;171:119-141. doi: 10.1016/B978-0-444-64239-4.00006-0.
Many neurologic diseases in women are influenced by the physiologic and hormonal changes of pregnancy, and pregnancy itself poses challenges in both treatment and evaluation of these conditions. Some diseases, such as epilepsy and multiple sclerosis, have a high enough prevalence in the young female population to support robust epidemiologic data while many other neurologic diseases, such as specific myopathies and muscular dystrophies, have a low prevalence, with data limited to case reports and small case series. This chapter features epidemiologic information regarding a breadth of neurologic conditions, including stroke, epilepsy, demyelinating disease, peripheral neuropathies, migraine, sleep-disordered breathing, and meningioma, in women in the preconception, pregnancy, and postpartum stages.
许多女性神经疾病受妊娠的生理和激素变化影响,妊娠本身在这些疾病的治疗和评估方面带来挑战。一些疾病,如癫痫和多发性硬化症,在年轻女性中的患病率较高,足以支持强有力的流行病学数据,而许多其他神经疾病,如特定的肌病和肌肉营养不良症,患病率较低,数据仅限于病例报告和小病例系列。本章介绍了一系列神经疾病的流行病学信息,包括女性在受孕前、妊娠和产后阶段的中风、癫痫、脱髓鞘疾病、周围神经病、偏头痛、睡眠呼吸障碍和脑膜瘤。