Hernández-Hermida Y, López-Muñoz N, Alós J I
Juan-Ignacio Alós, Servicio de Microbiología, Hospital Universitario de Getafe, Carretera de Toledo km 12,500, 28905 Getafe, Madrid, Spain.
Rev Esp Quimioter. 2020 Oct;33(5):379-382. doi: 10.37201/req/068.2020. Epub 2020 Aug 3.
The aim of the study wat to analyze the antibiotic susceptibility of the pathogens causing urinary tract infection (UTI) and to stratify the results in function of patient´s clinical and demographic dates.
The susceptibility of the pathogens isolated in the urine of 144 patients with UTI randomly chosen was analyzed. The results were stratified in function of sex, age, type of UTI, previous UTI and previous antibiotic treatment.
The susceptibility of the all isolates and of the Escherichia coli isolates was analyzed. There were significant differences between groups in function of sex (fluoroquinolones), age (cefuroxime, ertapenem and gentamicin), type of UTI (cefuroxime, cefotaxime, ertapenem and fluoroquinolones), previous UTI and previous antibiotic treatment (cefotaxime, fluoroquinolones and fosfomycin).
The use of clinical and demographic data according to population and local resistance epidemiology of the pathogen causing UTI may help to select an adequate empirical treatment for UTI.
本研究的目的是分析引起尿路感染（UTI）的病原体的抗生素敏感性，并根据患者的临床和人口统计学数据对结果进行分层。
分析了随机选取的144例UTI患者尿液中分离出的病原体的敏感性。结果根据性别、年龄、UTI类型、既往UTI史和既往抗生素治疗情况进行分层。
分析了所有分离株和大肠杆菌分离株的敏感性。在性别（氟喹诺酮类）、年龄（头孢呋辛、厄他培南和庆大霉素）、UTI类型（头孢呋辛、头孢噻肟、厄他培南和氟喹诺酮类）、既往UTI史和既往抗生素治疗情况（头孢噻肟、氟喹诺酮类和磷霉素）方面，各亚组之间存在显著差异。
根据引起UTI的病原体的人群和当地耐药流行病学，利用临床和人口统计学数据可能有助于选择合适的UTI经验性治疗方案。
