Schang J C, Dauchel J, Mendel C, Marescaux J, Hoff M O, Grenier J F
Pathol Biol (Paris). 1977 May;25(5):315-21.
Investigations we carried out in man and animals in order to study the relationships between the electrical and the mechanical activities of the intestine, and to precise the role of BER in the regulation of intestinal motility. In the dog, an intestinal movements transducer allowed to establish that spiking activities were concomitant with circular contractions, and that these two phenomena were rhythmed by the slow waves. Under basal conditions, the longitudinal movements occurred independently; under stimulation longitudinal movements occurred independently; under stimulation longitudinal relaxations were observed to correspond to circular contractions. In man, the post-laparotomy paralytic ileus provoked abnormalities in the BER which seemed to be related to a disturbance of the coordination of the motility, resulting in the absence of intraluminal propulsion. Administration of coherin, a postpituitary extract, was followed by a regularization of the BER and by a decrease of paralytic ileus duration. This confirms the important role of the BER in the myogenic regulation of the intestinal motility.
我们在人和动物身上进行了研究，以探讨肠道电活动与机械活动之间的关系，并明确基本电节律（BER）在肠道运动调节中的作用。在狗身上，一个肠道运动换能器证实，锋电位活动与环形收缩同时出现，且这两种现象都由慢波节律控制。在基础条件下，纵向运动独立发生；受到刺激时，纵向运动也独立发生；受到刺激时，观察到纵向松弛与环形收缩相对应。在人类中，剖腹术后麻痹性肠梗阻会引发基本电节律异常，这似乎与运动协调性紊乱有关，导致管腔内推进缺失。给予垂体后叶提取物相干素后，基本电节律恢复正常，麻痹性肠梗阻持续时间缩短。这证实了基本电节律在肠道运动肌源性调节中的重要作用。
