Department of Internal Medicine, Far Eastern Memorial Hospital, New Taipei City, Taiwan.
Department of Pathology, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
J Microbiol Immunol Infect. 2021 Dec;54(6):1154-1158. doi: 10.1016/j.jmii.2020.07.007. Epub 2020 Jul 23.
Leishmaniasis is prevalent in Southern Europe, the Middle East, India, Africa, and Central and South America. Cutaneous leishmaniasis may spontaneously heal over time without treatment; however, risk of visceral dissemination and the impact of cosmetic defect are important concerns. We report a Case of cutaneous leishmaniasis in a patient who ever traveled to Mexico before the onset of a deteriorating wound around the swollen left eyebrow. A diagnosis of infection with Leishmania mexicana was made based on histopathological examination and molecular identification. Systemic treatment with liposomal amphotericin B and ketoconazole were administered with gradual healing of the lesion. Also, this traveler case implicates that the spread of endemic parasitic diseases may be a concealed risk on the public health for Taiwan underlying globalization.
利什曼病流行于南欧、中东、印度、非洲以及中南美洲。皮肤利什曼病不经治疗可随时间自行痊愈；然而，内脏播散的风险和对美观的影响是重要关注点。我们报告一例曾前往墨西哥的患者出现左眉肿胀周围恶化性伤口时发生的皮肤利什曼病。根据组织病理学检查和分子鉴定，诊断为感染墨西哥利什曼原虫。给予脂质体两性霉素 B 和酮康唑全身治疗，病变逐渐愈合。此外，这例旅行者病例表明，全球化背景下，台湾地区的公共卫生可能面临着地方性寄生虫病传播这一隐藏风险。
