Department of Microbiology, Immunology and Parasitology, Faculty President Antônio Carlos-Porto Nacional, Tocantins, Brazil.
Faculty President Antônio Carlos-Porto Nacional, Tocantins, Brazil.
Am J Trop Med Hyg. 2018 Nov;99(5):1165-1169. doi: 10.4269/ajtmh.17-0760.
The disseminated form of leishmaniasis is a serious and rare disease, being diagnosed in 2% of the cutaneous cases registered per year in Brazil. The main characteristic is the appearance of multiple pleomorphic lesions on the cutaneous surface. A 68-year-old male from the rural area of Tocantins, Brazil, presented atypical disseminated cutaneous leishmaniasis (ACL). The clinical course and histopathological and immunological findings presented a mixed pattern that hindered diagnosis and therapeutic management. Molecular typing revealed a mixed infection with and . Molecular identification of the agents responsible for ACL is important for adequate therapeutic planning, minimizing the possibility of sequellae that impact the quality of life of the patient.
皮肤利什曼病的播散型是一种严重且罕见的疾病，在巴西每年登记的皮肤病例中，发病率占 2%。其主要特征是皮肤表面出现多个多形性病变。巴西托坎廷斯农村地区的一名 68 岁男性患者出现了非典型性皮肤播散性利什曼病（ACL）。临床表现、组织病理学和免疫学检查结果呈混合模式，这对诊断和治疗管理造成了阻碍。分子分型显示合并了 和 感染。ACL 致病因子的分子鉴定对于合理的治疗计划非常重要，可以最大程度地减少对患者生活质量产生影响的后遗症的发生。
