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[慢性卡他性牙龈炎患者在接受特效法西吉农治疗前后针对口腔毛滴虫的体液免疫反应]

[Humoral immune response against Trichomonas tenax in patients with chronic catarrhal gingivitis before and after specific Fasigyn treatment].

作者信息

Zvetkova A, Isev V, Stoilova R

出版信息

Stomatologiia (Sofiia). 1988 Mar-Apr;70(2):4-8.

PMID:3274183
Abstract

The following parameters were studied in 71 subjects, aged from 7 to 38 with chronic catarrhal gingivitis, invaded by T. tenax: oral-hygienic index of Green and Vermillion before the specific Fasigyn treatment and on 3, 7, 14 and 30 days after the treatment; the presence of complement-combining antibodies against T. tenax and the dynamics of antibody synthesis by 3, 6, 12 and 15 month after the treatment. Thirty one subjected with chronic catarrhal gingivitis, non invaded by T tenax were studied as controls. It has been established that in 53.52% of the subjects with chronic catarrhal gingivitis, invaded by T tenax, the inflammatory changes in gingiva disappeared as early as the third day after the specific Fasigyn treatment and in the rest--by 30 day. Higher values of complement-combining antibodies against T. tenax with a titre from 1:40 to 1:2569 were established in 65.34% from the subjects with chronic catarrhal gingivitis, invaded by T. tenax. The titre of antibodies sharpy decreased by month 3 and was normalized by months 6-12 after Fasigyn treatment.

摘要

对71名年龄在7至38岁、患有慢性卡他性牙龈炎且感染了口腔纤毛菌的受试者进行了以下参数研究:在进行特定的法西吉农治疗前以及治疗后3天、7天、14天和30天的格林和维米利恩口腔卫生指数;针对口腔纤毛菌的补体结合抗体的存在情况以及治疗后3个月、6个月、12个月和15个月抗体合成的动态变化。将31名患有慢性卡他性牙龈炎但未感染口腔纤毛菌的受试者作为对照进行研究。已确定,在53.52%感染口腔纤毛菌的慢性卡他性牙龈炎受试者中,牙龈的炎症变化在特定的法西吉农治疗后第三天就消失了,其余受试者在30天时消失。在65.34%感染口腔纤毛菌的慢性卡他性牙龈炎受试者中,针对口腔纤毛菌的补体结合抗体滴度较高,从1:40到1:2569。抗体滴度在治疗后3个月急剧下降,并在法西吉农治疗后6至12个月恢复正常。

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