Gao Wei, Ou Tong-Wen, Cui Xin, Wu Jiang-Tao, Cui Bo
Department of Urology, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.
World J Clin Cases. 2020 Jul 6;8(13):2841-2848. doi: 10.12998/wjcc.v8.i13.2841.
Retroperitoneal fibrosis is an exceptionally rare disease characterized by proliferation of fibrous tissue and inflammation in the retroperitoneum. It features many symptoms in the kidneys and in other organs and usually leads to ureteral obstruction.
Here we present 9 consecutive cases of idiopathic retroperitoneal fibrosis (IRPF) in patients who presented to the Department of Nephrology or Department of Rheumatology, Xuanwu Hospital, Capital Medical University, Beijing, China, between January 2012 and June 2017 with ureteral obstruction due to external compression of the ureter that led to hydronephrosis and kidney dysfunction. Computed tomography imaging was used to identify hydronephrosis and ureteral obstruction and to evaluate kidney function. Each patient was diagnosed with IRPF based on clinical observation and computed tomography examination results. To restore kidney function, a retrograde metallic stent was placed in the ureter under X-ray guidance 2 d after each patient's admission. No perioperative complications occurred in any patient, but postoperative complications occurred in two patients as follows: Patient 2 had stent migration and repeated metallic stent infections that resolved with treatment; and patient 4 had postoperative hematuria because he resumed normal activities too soon after stent placement (contrary to instruction). Placement of the metallic ureteral stents provided relief from ureteral obstruction and restored kidney function in all patients.
Our 9-case series underscores the utility and efficacy of applying the Resonance metallic ureteral stent to treat ureteral obstruction in patients with IRPF. For all retroperitoneal fibrosis cases in our series, ureteral stents provided effective relief and were shown to reduce the incidence rate of perioperative and postoperative complications.
腹膜后纤维化是一种极为罕见的疾病,其特征为腹膜后纤维组织增生和炎症。它在肾脏和其他器官有许多症状表现,通常会导致输尿管梗阻。
本文介绍了9例特发性腹膜后纤维化(IRPF)患者,这些患者于2012年1月至2017年6月期间就诊于中国北京首都医科大学宣武医院肾病科或风湿免疫科,因输尿管外部受压导致肾积水和肾功能障碍而出现输尿管梗阻。采用计算机断层扫描成像来识别肾积水和输尿管梗阻,并评估肾功能。根据临床观察和计算机断层扫描检查结果,每位患者均被诊断为IRPF。为恢复肾功能,每位患者入院2 d后在X线引导下于输尿管内放置逆行金属支架。所有患者均未发生围手术期并发症,但有2例患者出现术后并发症:病例2发生支架移位和反复金属支架感染,经治疗后缓解;病例4术后出现血尿,原因是支架置入后过早恢复正常活动(违反医嘱)。金属输尿管支架的置入缓解了所有患者的输尿管梗阻并恢复了肾功能。
我们的9例病例系列强调了应用共振金属输尿管支架治疗IRPF患者输尿管梗阻的实用性和有效性。对于我们系列中的所有腹膜后纤维化病例,输尿管支架提供了有效的缓解,并显示可降低围手术期和术后并发症的发生率。