Department of Ophthalmology, College of Medicine, CHA Bundang Medical Center, CHA University, #59 Yatap-ro, Bundang-gu, Seongnam, 13496, South Korea.
Graefes Arch Clin Exp Ophthalmol. 2021 Jan;259(1):173-180. doi: 10.1007/s00417-020-04833-2. Epub 2020 Aug 3.
To investigate the lacrimal drainage system (LDS) from the punctum to the inferior meatus and the clinical outcomes of transcanalicular endoscopic dacryoplasty and silicone intubation through dacryoendoscopy in patients with primary acquired nasolacrimal duct obstruction (PANDO).
We conducted a retrospective chart review of 203 cases from 156 patients who underwent dacryoendoscopy (FT-203F; Fibertech Co., Tokyo, Japan) and sheath-guided silicone intubation for PANDO from December 2014 to March 2018. Clinical characteristics, tear meniscus height, irrigation test, dacryocystographic findings, and dacryoendoscopic findings related to clinical factors and surgical outcomes were evaluated.
The study population consisted of 44 males and 119 females (mean age, 60.4 ± 13.6 years). The mean epiphora duration was 3.8 ± 4.8 years. Dacryoendoscopic findings revealed that the following factors were associated with LDS obstruction (% cases): mucus, 39.9%; fibrotic membrane, 19.2%; stones, 9.4%; granulation, 8.9%; and stenosis, 2.7%. The locations of obstruction were as follows (% cases): nasolacrimal duct, 35.7%; canaliculus, 33.0%; sac, 27.6%; and inferior meatus, 3.5%. The types of LDS obstruction were classified into two groups: secretory group (n = 118) that included mucus, stones, and granulation, and structural group (n = 85) associated with the membrane and stenosis; the pattern of them was divided into focal (n = 134) and diffuse (n = 76). The overall success rate was 86.2%. The success rate of the structural group (95.3%) was significantly higher than that of the secretory group (79.7%) (p = 0.001). All membranous obstruction cases at the inferior meatus were treated successfully, regardless of the irrigation test results. The success rate of the focal group (93.1%) was significantly higher than that of the diffuse group (74.0%) (p = 0.003).
Dacryoendoscopic findings were informative regarding the clinical factors leading to LDS in PANDO patients. Mucus and stones in the lacrimal sac were common findings of functional lacrimal duct obstruction. Membranous obstruction and stenosis could be managed by recanalization under direct visualization. Transcanalicular endoscopic dacryoplasty and silicone intubation is considered to be a safe and effective procedure, sparing the patient from bony destruction in selected cases of PANDO.
为了研究原发性获得性鼻泪管阻塞(PANDO)患者从泪点到下鼻道的泪液引流系统(LDS)以及经泪道内窥镜Transcanalicular 内镜鼻泪管成形术和硅胶插管的临床结果。
我们对 2014 年 12 月至 2018 年 3 月期间,156 例患者的 203 例经泪道内窥镜(FT-203F;Fibertech Co.,东京,日本)和鞘引导硅胶插管治疗 PANDO 的病例进行了回顾性图表分析。评估了与临床因素和手术结果相关的临床特征、泪膜高度、冲洗试验、泪道造影和泪道内窥镜检查结果。
研究人群包括 44 名男性和 119 名女性(平均年龄,60.4±13.6 岁)。平均溢泪持续时间为 3.8±4.8 年。泪道内窥镜检查结果显示,LDS 阻塞的以下因素与 LDS 阻塞有关(%病例):黏液,39.9%;纤维膜,19.2%;结石,9.4%;肉芽组织,8.9%;和狭窄,2.7%。阻塞的位置如下(%病例):鼻泪管,35.7%;泪小管,33.0%;囊,27.6%;和下鼻道,3.5%。LDS 阻塞的类型分为两组:分泌组(n=118),包括黏液、结石和肉芽组织;结构组(n=85)与膜和狭窄有关;模式分为局灶性(n=134)和弥漫性(n=76)。总体成功率为 86.2%。结构组(95.3%)的成功率明显高于分泌组(79.7%)(p=0.001)。所有下鼻道的膜性阻塞病例均成功治疗,无论冲洗试验结果如何。局灶性组(93.1%)的成功率明显高于弥漫性组(74.0%)(p=0.003)。
泪道内窥镜检查结果为 PANDO 患者导致 LDS 的临床因素提供了信息。泪囊中黏液和结石是功能性泪道阻塞的常见发现。在直接可视化下,可对膜性和狭窄性阻塞进行再通治疗。经泪道内窥镜 Transcanalicular 内镜鼻泪管成形术和硅胶插管被认为是一种安全有效的方法,可以避免在某些 PANDO 病例中造成骨质破坏。