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儿童期虐待与成年期赌博障碍:厘清因果和家庭影响。

Childhood maltreatment and disordered gambling in adulthood: disentangling causal and familial influences.

机构信息

Department of Psychological Sciences, University of Missouri, Columbia, MO, USA.

Queensland Institute of Medical Research-Berghofer, Herston, QLD, AUS.

出版信息

Psychol Med. 2022 Apr;52(5):979-988. doi: 10.1017/S0033291720002743. Epub 2020 Aug 3.

Abstract

BACKGROUND

Despite abundant research on the potential causal influence of childhood maltreatment (CM) on psychological maladaptation in adulthood, almost none has implemented the discordant twin design as a means of examining the role of such experiences in later disordered gambling (DG) while accounting for genetic and family environmental confounds. The present study implemented such an approach to disentangle the potential causal and familial factors that may account for the association between CM and DG.

METHODS

Participants were 3750 twins from the Australian Twin Registry [Mage = 37.60 (s.d. = 2.31); 58% female]. CM and DG were assessed separately via two semi-structured telephone interviews. Random-intercept generalized linear mixed models were fit to the data; zygosity, sex, educational attainment, childhood psychiatric disorder, adult antisocial behavior, and alcohol use disorder (AUD) were included as covariates.

RESULTS

Neither quasi-causal nor familial effects of CM predicted DG after adjusting for covariates. Educational attainment appeared to reduce the risk of DG while AUD appeared to increase risk; evidence also emerged for familial effects of antisocial behavior on DG. Post-hoc analyses revealed a familial effect of CM on antisocial behavior, indicating that the association between CM and DG identified in unadjusted models and in prior studies may be accounted for by genetic and shared family environmental effects of antisociality.

CONCLUSIONS

These findings add to the meager literature showing that CM does not exert a causal effect on DG, and present novel evidence that familial effects of antisocial behavior may account for the association between CM and DG identified in extant non-twin research.

摘要

背景

尽管有大量研究探讨了儿童期虐待(CM)对成年后心理适应不良的潜在因果影响,但几乎没有研究采用不和谐双胞胎设计来检验这些经历在后来的赌博障碍(DG)中的作用,同时考虑到遗传和家庭环境的混杂因素。本研究采用这种方法来厘清可能导致 CM 和 DG 之间关联的潜在因果和家庭因素。

方法

参与者是来自澳大利亚双胞胎登记处的 3750 对双胞胎[年龄=37.60(标准差=2.31);58%为女性]。通过两次半结构化电话访谈分别评估 CM 和 DG。随机截距广义线性混合模型拟合数据;同卵性、性别、教育程度、儿童期精神障碍、成年反社会行为和酒精使用障碍(AUD)作为协变量。

结果

在调整协变量后,CM 的准因果或家庭效应均不能预测 DG。教育程度似乎降低了 DG 的风险,而 AUD 似乎增加了风险;反社会行为对 DG 的家庭效应也有证据。事后分析显示 CM 对反社会行为有家庭效应,这表明未经调整模型和先前研究中确定的 CM 与 DG 之间的关联可能是由反社会性的遗传和共同家庭环境效应所解释。

结论

这些发现增加了表明 CM 对 DG 没有因果影响的文献,并提供了新的证据表明反社会行为的家庭效应可能解释了现存非双胞胎研究中确定的 CM 与 DG 之间的关联。

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Child maltreatment and problem gambling: A systematic review.儿童虐待与问题赌博:一项系统综述。
Child Abuse Negl. 2016 Aug;58:24-38. doi: 10.1016/j.chiabu.2016.06.003. Epub 2016 Jun 20.

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