Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, Barwon Health, Geelong, Australia.
Deakin University, IMPACT - the Institute for Mental and Physical Health and Clinical Translation, Barwon Health, Geelong, Australia; Department of Medicine-Western Campus, the University of Melbourne, St Albans, Australia; University Hospital Geelong, Barwon Health, Geelong, Australia.
Cancer Epidemiol. 2020 Oct;68:101790. doi: 10.1016/j.canep.2020.101790. Epub 2020 Jul 31.
Determining the validity of self-reported data is important. The aim of this study was to assess the validity of self-reported cancer and investigate factors associated with accurate reporting in men and women.
Study participants (n = 1727) from the Geelong Osteoporosis Study, located in south-eastern Australia, were utilised. Self-reported cancer data were compared to Victorian Cancer Registry records. Age, socioeconomic status (SES), education and time between cancer diagnosis and study appointment were investigated as factors associated with accuracy of self-report.
There were 142 participants who self-reported a cancer and 135 with a VCR record. Comparing self-report to any registry record, sensitivity was 63.7 %, specificity 96.5 %, PPV 60.6 %, NPV 96.9 %, and overall agreement ĸ0.588. Comparing exact-match records, sensitivity was 58.8 %, specificity 95.5 %, PPV 49.3 %, NPV 96.9 % and overall agreement ĸ0.499. In logistic regression models, post-secondary education was independently associated with accuracy of any (OR 1.72, 95 % CI 1.10-2.70) and exact-match (OR 1.59, 95 % CI 1.05-2.42) self-report, compared to cancer registry record. For any cancer, being aged >70 years was inversely associated with accuracy (OR 0.24, 95 % CI 0.15-0.38). Likewise, for matched cancer reporting, those aged 60-70 years (OR 0.51, 95 %CI 0.30-0.88) and >70 years (OR 0.23, 95 % CI 0.15-0.35) were less accurate. No other significant associations were detected.
Results suggest moderate agreement between self-report and registry data for any cancer among men and women. However, when comparing self-report to registry data for exact-match cancer type, level of overall agreement deteriorated. Self-report cancer data may be acceptable for determining a history of cancer, although, is less accurate in identifying history of specific cancer types documented in registry-based data.
确定自我报告数据的有效性很重要。本研究旨在评估自我报告癌症的有效性，并调查男性和女性中与准确报告相关的因素。
本研究利用了位于澳大利亚东南部的 Geelong Osteoporosis Study 的 1727 名研究参与者。将自我报告的癌症数据与维多利亚癌症登记处的记录进行比较。研究了年龄、社会经济地位 (SES)、教育程度以及癌症诊断和研究预约之间的时间间隔等因素与自我报告准确性的关系。
共有 142 名参与者自我报告患有癌症，135 名参与者有 VCR 记录。将自我报告与任何登记处记录进行比较，敏感性为 63.7%，特异性为 96.5%，PPV 为 60.6%，NPV 为 96.9%，总体一致性为 κ0.588。将完全匹配的记录进行比较，敏感性为 58.8%，特异性为 95.5%，PPV 为 49.3%，NPV 为 96.9%，总体一致性为 κ0.499。在逻辑回归模型中，接受过高等教育与任何（OR 1.72，95%CI 1.10-2.70）和完全匹配（OR 1.59，95%CI 1.05-2.42）自我报告的准确性独立相关，而不是癌症登记处的记录。对于任何癌症，年龄>70 岁与准确性呈负相关（OR 0.24，95%CI 0.15-0.38）。同样，对于匹配的癌症报告，年龄在 60-70 岁（OR 0.51，95%CI 0.30-0.88）和>70 岁（OR 0.23，95%CI 0.15-0.35）的人准确性较低。未发现其他显著关联。
结果表明，男性和女性的自我报告和登记数据之间存在中度一致性，但当将自我报告与登记数据中确切匹配的癌症类型进行比较时，总体一致性水平恶化。尽管自我报告癌症数据可能足以确定癌症病史，但在识别登记处数据中记录的特定癌症类型的病史方面，准确性较低。
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