Procz Simon, Roque Gerardo, Avila Carlos, Racedo Jorge, Rueda Roberto, Santos Ivan, Fiederle Michael
IEEE Trans Med Imaging. 2020 Dec;39(12):3766-3778. doi: 10.1109/TMI.2020.3004648. Epub 2020 Nov 30.
Despite the benefits of mammography investigations, some studies have shown that X-ray exposure from the mammography screening itself can statistically cause breast cancer in a small fraction of women. Therefore, a dose reduction in mammography is desirable. At the same time, there is a demand for a higher spatial resolution in mammographic imaging. The most promising way to achieve these goals is the use of advanced photon-processing semiconductor X-ray detectors with optimum sensor materials. This study addresses the investigation of the optimum semiconductor sensor material for mammography in combination with the photon-processing detector Medipix3RX. The influence of K-shell fluorescence from the sensor material on the achievable contrast-to-noise ratio is investigated, as well as the attenuation efficiency. The three different sensor materials, CdTe, GaAs, and Si are studied, showing advances of CdTe-sensors for mammography. Furthermore, a comparison of the contrast-to-noise ratio between a clinical Se-detector and Medipix3RX detectors with Si- and CdTe-sensors is shown using a self-produced mammography phantom that is based on real human tissue.
尽管乳腺钼靶检查有诸多益处，但一些研究表明，乳腺钼靶筛查本身产生的X射线照射在统计学上会导致一小部分女性患乳腺癌。因此，降低乳腺钼靶检查的剂量是很有必要的。与此同时，对乳腺钼靶成像的空间分辨率也有更高的要求。实现这些目标最有前景的方法是使用具有最佳传感器材料的先进光子处理半导体X射线探测器。本研究探讨了结合光子处理探测器Medipix3RX用于乳腺钼靶检查的最佳半导体传感器材料。研究了传感器材料的K壳层荧光对可实现的对比度噪声比的影响以及衰减效率。研究了三种不同的传感器材料，碲化镉（CdTe）、砷化镓（GaAs）和硅（Si），结果表明碲化镉传感器在乳腺钼靶检查方面具有优势。此外，使用基于真实人体组织自制的乳腺钼靶体模，展示了临床硒探测器与配备硅和碲化镉传感器的Medipix3RX探测器之间对比度噪声比的比较。
