人类基因命名准则。
Guidelines for human gene nomenclature.
机构信息
HUGO Gene Nomenclature Committee (HGNC), European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton, UK.
Department of Haematology, University of Cambridge School of Clinical Medicine, Cambridge, UK.
出版信息
Nat Genet. 2020 Aug;52(8):754-758. doi: 10.1038/s41588-020-0669-3.
Abstract
Standardized gene naming is crucial for effective communication about genes, and as genomics becomes increasingly important in healthcare, the need for a consistent language for human genes becomes ever more vital. Here we present the current HUGO Gene Nomenclature Committee (HGNC) guidelines for naming not only protein-coding but also RNA genes and pseudogenes, and outline the changes in approach and ethos that have resulted from the discoveries of the last few decades.
摘要
标准化的基因命名对于有效交流基因信息至关重要，随着基因组学在医疗保健中的重要性日益增加，对于人类基因使用一致的语言变得更加重要。在此，我们介绍了当前人类基因命名委员会（HGNC）的命名指南，不仅适用于编码蛋白的基因，还适用于 RNA 基因和假基因，并概述了过去几十年的发现带来的方法和理念上的变化。
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