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Investigating the effects of tDCS on Visual Orientation Discrimination Task Performance: 'The possible influence of placebo'.

作者信息

BinDawood A, Dickinson A, Aytemur A, Howarth C, Milne E, Jones M

机构信息

Department of Psychology, University of Sheffield, Cathedral Court, 1 Vicar Lane, Sheffield UK, S1 2LT.

Department of Psychology, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Cogn Enhanc. 2020 Sep;4(3):235-249. doi: 10.1007/s41465-019-00154-3. Epub 2019 Nov 9.


DOI:10.1007/s41465-019-00154-3
PMID:32747876
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7115888/
Abstract

The non-invasive neuromodulation technique tDCS offers the promise of a low cost tool for both research and clinical applications in psychology, psychiatry and neuroscience. However, findings regarding its efficacy are often equivocal. A key issue is that the clinical and cognitive applications studied are often complex and thus effects of tDCS are difficult to predict given its known effects on the basic underlying neurophysiology, namely alterations in cortical inhibition-excitation balance. As such, it may be beneficial to assess the effects of tDCS in tasks whose performance has a clear link to cortical inhibition-excitation balance such as the visual orientation discrimination task (ODT). In prior studies in our laboratory no practise effects were found during 2 consecutive runs of the ODT, thus in the current investigation, to examine the effects of tDCS, subjects received 10 minutes of 2mA occipital tDCS (sham, anode, cathode) between a first and second run of ODT. Surprisingly, subjects' performance significantly improved in the second run of ODT compared to the first one regardless of the tDCS stimulation type they received (anodal, cathodal, or sham-tDCS). Possible causes for such an improvement could have been due to either a generic 'placebo' effect of tDCS (as all subjects received some form of tDCS) or an increased delay period between the two runs of ODT of the current study compared to our previous work (10 minutes duration required to administer tDCS as opposed to ~2 minutes in previous studies as a 'break'). As such, we tested these two possibilities with a subsequent experiment in which subjects received 2 minutes or 10 minutes delay between the 2 runs (with no tDCS) or 10 minutes of sham-tDCS. Only sham-tDCS resulted in improved performance thus these data add to a growing literature suggesting that tDCS has powerful placebo effect that may occur even in the absence of active cortical modulation.

摘要

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Investigating the effects of tDCS on Visual Orientation Discrimination Task Performance: 'The possible influence of placebo'.

J Cogn Enhanc. 2020-9

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引用本文的文献

[1]
TDCS over PPC or DLPFC does not improve visual working memory capacity.

Commun Psychol. 2024-3-11

[2]
The Effects of Transcranial Direct Current Stimulation in Patients with Mild Cognitive Impairment.

Neurol Int. 2023-11-29

[3]
Reverse effect of home-use binaural beats brain stimulation.

Sci Rep. 2023-7-8

[4]
Attention neuroenhancement through tDCS or neurofeedback: a randomized, single-blind, controlled trial.

Sci Rep. 2022-10-20

[5]
Non-invasive brain stimulation and neuroenhancement.

Clin Neurophysiol Pract. 2022-5-25

[6]
Effects of Prefrontal Transcranial Direct Current Stimulation on Retention of Performance Gains on an Obstacle Negotiation Task in Older Adults.

Neuromodulation. 2023-6

[7]
Blinding in tDCS Studies: Correct End-of-Study Guess Does Not Moderate the Effects on Associative and Working Memory.

Brain Sci. 2021-12-31

[8]
The Role of Expectation and Beliefs on the Effects of Non-Invasive Brain Stimulation.

Brain Sci. 2021-11-18

[9]
Effectiveness of noninvasive brain stimulation in the treatment of anxiety disorders: a meta-analysis of sham or behaviour-controlled studies.

J Psychiatry Neurosci. 2021

[10]
Individual Cerebral Blood Flow Responses to Transcranial Direct Current Stimulation at Various Intensities.

Brain Sci. 2020-11-13

本文引用的文献

[1]
The time course of ineffective sham-blinding during low-intensity (1 mA) transcranial direct current stimulation.

Eur J Neurosci. 2019-7-8

[2]
A Rapid Form of Offline Consolidation in Skill Learning.

Curr Biol. 2019-3-28

[3]
Sham tDCS: A hidden source of variability? Reflections for further blinded, controlled trials.

Brain Stimul. 2019-1-2

[4]
The effect of expectation on transcranial direct current stimulation (tDCS) to suppress food craving and eating in individuals with overweight and obesity.

Appetite. 2019-1-3

[5]
Evidence for Cognitive Placebo and Nocebo Effects in Healthy Individuals.

Sci Rep. 2018-11-28

[6]
Effects of High-Definition and Conventional Transcranial Direct-Current Stimulation on Motor Learning in Children.

Front Neurosci. 2018-10-31

[7]
Opposite Dynamics of GABA and Glutamate Levels in the Occipital Cortex during Visual Processing.

J Neurosci. 2018-10-3

[8]
Physiology of Transcranial Direct Current Stimulation.

J ECT. 2018-9

[9]
Effects of transcranial direct current stimulation over the Broca's area on tongue twister production.

Int J Speech Lang Pathol. 2019-4

[10]
The use of tDCS as a therapeutic option for tinnitus: a systematic review.

Braz J Otorhinolaryngol. 2018-3-9

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