Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Nat Prod Res. 2021 Dec;35(24):5894-5898. doi: 10.1080/14786419.2020.1800698. Epub 2020 Aug 4.
The content of atropine and scopolamine is known to vary with ontogeny and plant organs selected which makes it necessary to define the optimal stage for harvesting of each plant organ. The present study aims at investigating the effect of ontogeny on the accumulation of atropine and scopolamine in the leaves, stems, roots, flowers and fruits of the Solanaceae plants Bercht. & J.Presl, L. L., Mill. and L. Results showed that the highest content of atropine and scopolamine was observed during the flowering stage of most organs. L. leaves collected during flowering stage exhibited the highest content of atropine (746.66 ug/g) followed by the pre-flowering leaves of L. and the flowering stage stems of L. while Mill. pre-flowering leaves and flowering stems had significantly higher content of scopolamine among all the tested extracts with a concentration of 555.04 ug/g and 244.26 ug/g, respectively.
莨菪和东莨菪碱的含量已知随个体发生和选择的植物器官而变化，这使得有必要确定每种植物器官的最佳收获阶段。本研究旨在调查个体发生对茄科植物 Bercht. & J.Presl，L. L.，Mill. 和 L.中莨菪碱和东莨菪碱积累的影响。结果表明，大多数器官在开花期观察到最高的阿托品和东莨菪碱含量。在开花期采集的 L. 叶片表现出最高的阿托品含量（746.66ug/g），其次是 L.的预开花叶片和 L.的开花期茎，而 M ill.的预开花叶片和开花期茎在所有测试提取物中具有更高的东莨菪碱含量，浓度分别为 555.04ug/g 和 244.26ug/g。
