University Hospital of Nephrology, University SS "Cyril and Methodius", Skopje, Macedonia.
University Hospital for Pediatric Disease, University SS "Cyril and Methodius", Skopje, Macedonia.
Ther Apher Dial. 2021 Jun;25(3):273-281. doi: 10.1111/1744-9987.13570. Epub 2020 Aug 24.
An arteriovenous fistula (AVF) remains the best choice of vascular access (VA) for hemodialysis (HD). The aim of the study was to determine the factors associated with the achievement of adequate blood flow (BF) of AVFs at the 4th week after creation. Created AVFs in 63 patients with chronic kidney disease (CKD) stage 4/5 and CKD stage 5 on hemodialysis (CKD5D) were analyzed in a prospective study. Doppler ultrasound (DUS) was used for measuring the diameter of the radial artery, the brachial artery and the cephalic vein before AVF creation. The BF of AVF was calculated by DUS at the 4th week after creation and adequate BF was defined as ≥ 600 mL/min. The average age of patients was 61.31 ± 12.9 years. An adequate BF of AVF at the 4th week after creation was achieved in 43.54% of patients. The BF of AVF measured in male patients was significantly higher compared to the BF of AVF obtained in females (576.03 mL/min vs 375.12 mL/min, P = 0.004). The diameter of the blood vessels with achieved adequate BF was significantly larger compared to the diameter of the blood vessels without adequate BF (radial artery: 2.45 mm vs 2.03 mm, P = 0.000; brachial artery: 4.78 mm vs 4.06 mm, P = 0.001 and cephalic vein: 3.12 mm vs 2.83 mm P = 0.018). The gender and the diameter of the blood vessels before AVF creation were significantly associated with achievement of adequate BF of AVF at the 4th week of creation.
动静脉瘘(AVF)仍然是血液透析(HD)血管通路的最佳选择。本研究旨在确定创建后第 4 周 AVF 达到足够血流量(BF)的相关因素。在一项前瞻性研究中,对 63 例慢性肾脏病(CKD)4/5 期和 CKD5D 患者的 AVF 进行了分析。在 AVF 创建前,使用多普勒超声(DUS)测量桡动脉、肱动脉和头静脉的直径。在创建后第 4 周,通过 DUS 测量 AVF 的 BF,并将足够的 BF 定义为≥600mL/min。患者的平均年龄为 61.31±12.9 岁。在第 4 周后,有 43.54%的患者实现了足够的 AVF BF。与女性患者相比,男性患者的 AVF BF 明显更高(576.03mL/min 比 375.12mL/min,P=0.004)。实现足够 BF 的血管的直径明显大于未达到足够 BF 的血管的直径(桡动脉:2.45mm 比 2.03mm,P=0.000;肱动脉:4.78mm 比 4.06mm,P=0.001 和头静脉:3.12mm 比 2.83mm,P=0.018)。性别和 AVF 创建前的血管直径与创建后第 4 周 AVF 达到足够 BF 显著相关。