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1890 例危重新冠肺炎患者行气管切开术的结局:西班牙全国队列研究。

Outcome of 1890 tracheostomies for critical COVID-19 patients: a national cohort study in Spain.

机构信息

Department of Otorhinolaryngology, Hospital Universitario El Bierzo, Médicos sin Fronteras s/n, 24401, Ponferrada, León, Spain.

Department of Medicine, Surgery and Anatomy, University of León, León, Spain.

出版信息

Eur Arch Otorhinolaryngol. 2021 May;278(5):1605-1612. doi: 10.1007/s00405-020-06220-3. Epub 2020 Aug 4.

DOI:10.1007/s00405-020-06220-3
PMID:32749607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7399582/
Abstract

BACKGROUND

The question of an optimal strategy and outcomes in COVID-19 tracheostomy has not been answered yet. The critical focus in our case study is to evaluate the outcomes of tracheostomy on intubated COVID-19 patients.

METHODS

A multicentric prospective observational study of 1890 COVID-19 patients undergoing tracheostomy across 120 hospitals was conducted over 7 weeks in Spain (March 28 to May 15, 2020). Data were collected with an innovative approach: instant messaging via WhatsApp.

OUTCOME MEASUREMENTS

complications, achieved weaning and decannulation and survival.

RESULTS

We performed 1,461 surgical (81.3%) and 429 percutaneous tracheostomies. Median timing of tracheostomy was 12 days (4-42 days) since orotracheal intubation. A close follow-up of 1616/1890 (85.5%) patients at the cut-off time of 1-month follow-up showed that in 842 (52.1%) patients, weaning was achieved, while 391 (24.2%) were still under mechanical ventilation and 383 (23.7%) patients had died from COVID-19. Decannulation among those in whom weaning was successful (n = 842) was achieved in 683 (81%) patients.

CONCLUSION

To the best of our knowledge, this is the largest cohort of COVID-19 patients undergoing tracheostomy. The critical focus is the unprecedented amount of tracheostomies: 1890 in 7 weeks. Weaning could be achieved in over half of the patients with follow-up. Almost one out of four tracheotomized patients died from COVID-19.

摘要

背景

COVID-19 气管切开术的最佳策略和结果仍未得到解答。在我们的病例研究中,关键重点是评估气管切开术对插管 COVID-19 患者的结果。

方法

对西班牙 120 家医院的 1890 例 COVID-19 患者进行了为期 7 周的多中心前瞻性观察性研究(2020 年 3 月 28 日至 5 月 15 日)。通过即时通讯应用程序 WhatsApp 以创新的方式收集数据。

结果测量

并发症、脱机和拔管以及存活率。

结果

我们进行了 1461 例手术(81.3%)和 429 例经皮气管切开术。气管切开术的中位时间是从气管插管开始的 12 天(4-42 天)。在 1 个月随访的截止时间对 1890 例患者中的 1616 例(85.5%)进行了密切随访,结果显示在 842 例(52.1%)患者中成功脱机,而 391 例(24.2%)仍在机械通气下,383 例(23.7%)患者死于 COVID-19。在成功脱机的 842 例患者中,有 683 例(81%)患者成功拔管。

结论

据我们所知,这是最大的 COVID-19 患者气管切开术队列。重点是史无前例数量的气管切开术:7 周内 1890 例。在随访的患者中,超过一半的患者可以成功脱机。将近四分之一的气管切开患者死于 COVID-19。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/5de82b2ae437/405_2020_6220_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/62a20cc775e7/405_2020_6220_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/1186ab6ed5e0/405_2020_6220_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/d6663bfa873b/405_2020_6220_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/5de82b2ae437/405_2020_6220_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/62a20cc775e7/405_2020_6220_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/1186ab6ed5e0/405_2020_6220_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/d6663bfa873b/405_2020_6220_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6b86/7399582/5de82b2ae437/405_2020_6220_Fig4_HTML.jpg

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