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基于脑桥静脉详细数值模型的硬膜下血肿预测

Prediction of subdural haematoma based on a detailed numerical model of the cerebral bridging veins.

作者信息

Costa José M C, Fernandes Fábio A O, Alves de Sousa Ricardo J

机构信息

Centre for Mechanical Technology and Automation, Mechanical Engineering Department, University of Aveiro, 3810-193, Aveiro, Portugal.

Centre for Mechanical Technology and Automation, Mechanical Engineering Department, University of Aveiro, 3810-193, Aveiro, Portugal.

出版信息

J Mech Behav Biomed Mater. 2020 Nov;111:103976. doi: 10.1016/j.jmbbm.2020.103976. Epub 2020 Jul 28.

Abstract

Traumatic brain injury is one of the major causes of death and disability in the world. One of the most frequent and deadly injury resulted from a head trauma is acute subdural haematoma (ASDH), which consists on the rupture of a bridging vein (BV). Given the importance of this type of injury, it is necessary to correctly assess thresholds and damage criteria, which is difficult to perform on human cadavers or animals, due to ethical and economical issues. Finite element (FE) models are a very good and cost-effective alternative. Once properly validated, a finite element head model (FEHM) becomes a valuable tool, that can be used in the development of head protective gear as a design tool and in the reconstruction of head traumas by predicting brain injuries under impact conditions. The YEt Another Head Model (YEAHM) is one example of a FE model that can be used to assist/replace the experimental tests. In this study, the bridging veins model from YEAHM was improved and validated by comparing its results with others reported in literature and estimating the success rate. At the end, it was developed a pressurised tubular shaped FE model of BVs, considering the blood pressure in cerebral veins. Results showed a maximum success rate of 90%, which in comparison with other FE models available in the literature, presents an equal or even better ASDH prediction success rate.

摘要

创伤性脑损伤是全球死亡和残疾的主要原因之一。头部外伤导致的最常见且致命的损伤之一是急性硬膜下血肿(ASDH),它是由桥静脉(BV)破裂引起的。鉴于这类损伤的重要性,有必要正确评估阈值和损伤标准,但由于伦理和经济问题,在人体尸体或动物身上进行此类评估很困难。有限元(FE)模型是一种非常好且具有成本效益的替代方法。一旦经过适当验证,有限元头部模型(FEHM)就成为一种有价值的工具,可用于头部防护装备的开发,作为设计工具,并通过预测撞击条件下的脑损伤来重建头部创伤。“另一个头部模型”(YEAHM)就是一个可用于辅助/替代实验测试的有限元模型的例子。在本研究中,通过将YEAHM的桥静脉模型结果与文献中报道的其他结果进行比较并估计成功率,对其进行了改进和验证。最后,考虑到脑静脉中的血压,开发了一种加压管状的桥静脉有限元模型。结果显示最大成功率为90%,与文献中其他可用的有限元模型相比,其急性硬膜下血肿预测成功率相同甚至更高。

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