Lanza Gaetano Antonio, Golino Michele, Villano Angelo, Lanza Oreste, Lamendola Priscilla, Fusco Augusto, Leggio Massimo
Fondazione Policlinico Universitario A. Gemelli IRCCS, 00168 Rome, Italy.
Department of Cardiovascular Medicine, Università Cattolica del S. Cuore, 00168 Rome, Italy.
J Clin Med. 2020 Aug 3;9(8):2487. doi: 10.3390/jcm9082487.
Endothelial dysfunction is an early abnormality in the process of atherosclerosis and cardiovascular disease and has been associated with worse clinical outcome. Cardiac rehabilitation (CR) has been reported to be helpful to reduce cardiovascular events in various types of cardiac disease, but the mechanisms of its beneficial effects remain only partially known. In this article, we review the studies that assessed the effect of CR on endothelial function in patients with various cardiac conditions. Available data show that CR significantly improves impaired endothelial function in these patients, which may contribute to the beneficial effects of CR on clinical outcome.
内皮功能障碍是动脉粥样硬化和心血管疾病进程中的早期异常，并且与较差的临床结局相关。据报道，心脏康复（CR）有助于减少各类心脏病患者的心血管事件，但其有益作用的机制仍仅部分为人所知。在本文中，我们综述了评估CR对各种心脏疾病患者内皮功能影响的研究。现有数据表明，CR可显著改善这些患者受损的内皮功能，这可能是CR对临床结局产生有益作用的原因。
