Bartholin Institutetet, Rigshospitalet, Copenhagen, Denmark.
Med Hypotheses. 2020 Oct;143:110127. doi: 10.1016/j.mehy.2020.110127. Epub 2020 Jul 21.
Fenofibrate, which is a PPAR-alfpha agonist, increases the level of sulfatide. In this letter we hypothesize on the background of various findings that this is beneficial against COVID-19. Fenofibrate has been used for decades against hypercholesterolemia and has no serious side effects. Therefore, a trial giving fenofibrate to patients with corona virus infection is recommended.
非诺贝特是一种过氧化物酶体增殖物激活受体-α激动剂，可增加硫酸酯的水平。在这封信中，我们根据各种发现提出假设，认为这对 COVID-19 有益。非诺贝特已被用于治疗高胆固醇血症数十年，且没有严重的副作用。因此，建议对冠状病毒感染患者给予非诺贝特进行试验。
