Department of Pediatrics, National Hospital Organization Beppu Medical Center, 1473 Oaza-Uchikamado, Beppu, Oita 874-0011, Japan.
Department of Pediatrics, National Hospital Organization Beppu Medical Center, 1473 Oaza-Uchikamado, Beppu, Oita 874-0011, Japan.
Epilepsy Behav. 2020 Oct;111:107306. doi: 10.1016/j.yebeh.2020.107306. Epub 2020 Jul 29.
The objective of this study was to investigate the association between the weather and epidemic condition and risk of febrile seizures (FSs) in Japan.
This single-center, retrospective study included 560 children (age, 6-60 months) with FSs who were transported to our center by ambulance from January 2011 through December 2018. The weather (temperature, atmospheric pressure, relative air humidity, amount of rainfall, sunshine duration, and air concentration of nitrogen dioxide [NO] and sulfur dioxide [SO]) and epidemic (influenza virus infection, infectious gastroenteritis, and exanthem subitum) conditions in this region were compared between the periods (days or weeks) with the transportation of children with FS to our hospital and those without such transportation.
In the univariate analyses, neither daily or weekly weather condition nor weekly epidemic condition was correlated to FS transportation. Furthermore, the multiple logistic regression analysis suggested that epidemic influenza virus infection (odds ratio [OR], 1.34; 95% confidence interval [CI], 1.08-1.73) and infectious gastroenteritis (OR, 1.64; 95% CI, 1.09-2.54) were the independent risk factors for FS occurrence and weather condition was not associated with FS risk.
Febrile seizure incidence may be increased by epidemic febrile infections but not by weather condition.
本研究旨在探讨日本天气和流行病情与热性惊厥（FS）发病风险之间的关联。
本单中心回顾性研究纳入了 2011 年 1 月至 2018 年 12 月期间因 FS 由救护车转运至我院的 560 例（年龄 6-60 个月）患儿。比较了患儿转运至我院的时期（日或周）与无转运时期该地区的天气（温度、大气压、相对空气湿度、降雨量、日照时间、二氧化氮[NO]和二氧化硫[SO]的空气浓度）和流行病情（流感病毒感染、传染性肠胃炎和出疹性疾病）状况。
在单因素分析中，每日或每周的天气状况或每周的流行病情均与 FS 转运无相关性。此外，多元逻辑回归分析表明，流行的流感病毒感染（比值比[OR]，1.34；95%置信区间[CI]，1.08-1.73）和传染性肠胃炎（OR，1.64；95%CI，1.09-2.54）是 FS 发作的独立危险因素，而天气状况与 FS 风险无关。
FS 发病率可能因流行的发热性感染而增加，但与天气状况无关。
