Nayak Arun Harishchandra, Kapote Deepali Swapnil, Fonseca Michelle, Chavan Niranjan, Mayekar Rahul, Sarmalkar Meenal, Bawa Amarjeet
Department of Obstetrics and Gynaecology, Lokmanya Tilak Medical College, Mumbai, India.
Lokmanya Tilak Medical College, Mumbai, India.
J Obstet Gynaecol India. 2020 Aug;70(4):256-261. doi: 10.1007/s13224-020-01335-3. Epub 2020 Jul 7.
The novel coronavirus disease (COVID-19) is the most challenging health crisis that we are facing today. Against the backdrop of this pandemic, it becomes imperative to study the effects of this infection on pregnancy and its outcome. Hence, the present study was undertaken to evaluate the effects of COVID-19 infection on the maternal morbidity and mortality, the course of labour as well as the neonatal outcome.
A total of 977 pregnant women were included in the study, from 1st April to 15th May 2020 at a tertiary care hospital. There were 141 women who tested COVID positive and remaining 836 patients were included in the COVID negative group. Findings were compared in both the groups.
The incidence of COVID positive pregnant women was found to be 14.43%. More patients delivered by LSCS in the COVID positive and the COVID negative group (50%) as compared to COVID negative group (47%), ( > 0.05). Low APGAR score (0-3) was observed in 2(1.52%) neonates of COVID positive mothers and in 15 (1.91%) neonates of COVID negative mothers. Overall most of the babies were healthy. Out of all babies tested, 3 were detected positive initially which were retested on day 5 and were found to be negative.
There is no significant effect of COVID infection on maternal and foetal outcome in pregnancy and there is no evidence of vertical transmission of the COVID-19 infection but long-term follow-up of these babies is recommended.
新型冠状病毒病（COVID-19）是我们当今面临的最具挑战性的健康危机。在这场大流行的背景下，研究这种感染对妊娠及其结局的影响变得势在必行。因此，本研究旨在评估COVID-19感染对孕产妇发病率和死亡率、分娩过程以及新生儿结局的影响。
2020年4月1日至5月15日，一家三级护理医院共纳入977名孕妇。其中141名妇女COVID检测呈阳性，其余836名患者被纳入COVID阴性组。对两组的研究结果进行比较。
COVID阳性孕妇的发生率为14.43%。与COVID阴性组（47%）相比，COVID阳性组和COVID阴性组通过剖宫产分娩的患者更多（50%），（P>0.05）。COVID阳性母亲的2名（1.52%）新生儿和COVID阴性母亲的15名（1.91%）新生儿出现低阿氏评分（0 - 3分）。总体而言，大多数婴儿健康。在所有检测的婴儿中，最初有3名检测呈阳性，在第5天重新检测后呈阴性。
COVID感染对妊娠期间的孕产妇和胎儿结局没有显著影响，也没有证据表明存在COVID-19感染的垂直传播，但建议对这些婴儿进行长期随访。
