Takashina T, Kanda Y, Tsumura N, Hayakawa O, Tanaka S, Ito E
Department of Obstetrics and Gynecology, Sapporo Medical College, Hokkaido, Japan.
Acta Cytol. 1988 Jan-Feb;32(1):109-12.
Surgical vaginal reconstruction was performed by a free skin graft in two patients without a vagina. The postoperative changes in vaginal smears collected from the artificial vaginas were observed for about two years. Marked operation-induced inflammatory changes were observed until the second postoperative month. After the third postoperative month, the background became relatively clear. Cyanophilic and eosinophilic superficial cells, intermediate cells and Döderlein bacilli were observed occasionally in addition to keratotic cells. Six to 12 months after surgery, the vaginal smears showed little abnormality, except for the presence of keratotic cells. The changes in the vaginal smears after the third month show that the artificial vaginal epithelium changed cytologically to an almost normal vaginal mucosa that, although not histologically complete, responded to hormones. The presence of Döderlein bacilli suggests that the regional environment of the artificial vagina was almost the same as that of the normal vagina.
对两名无阴道患者采用游离皮片移植进行手术阴道重建。对从人工阴道采集的阴道涂片术后变化进行了约两年的观察。直到术后第二个月，观察到明显的手术诱发炎症变化。术后第三个月后，背景相对清晰。除角化细胞外，偶尔还观察到嗜蓝和嗜酸性表层细胞、中间细胞及杜氏杆菌。术后6至12个月，阴道涂片除角化细胞外几乎无异常。第三个月后的阴道涂片变化表明，人工阴道上皮在细胞学上转变为几乎正常的阴道黏膜，虽然在组织学上并不完整，但对激素有反应。杜氏杆菌的存在表明人工阴道的局部环境与正常阴道几乎相同。
