Daugaard H O, Thomsen A C, Henriques U, Ostergaard A
Department of Obstetrics and Gynecology, University Hospital, Aarhus, Denmark.
Am J Obstet Gynecol. 1988 Jan;158(1):28-31. doi: 10.1016/0002-9378(88)90769-7.
The occurrence of group B streptococci in the lower urogenital tract of 150 women with signs of abortion and 100 women with uncomplicated pregnancy was studied. Group B streptococci appeared significantly more frequently in the urine (p less than 0.001) and in the uterine cervix (p less than 0.01) of women with abortion. Delivery resulted in 85% of patients with group B streptococci in the urine and in 42% of patients with no group B streptococci (p less than 0.001). Group B streptococci were cultured from amniotic fluid from three of eight women with intact membranes and were isolated from the urine and cervix. These bacteria were antibody coated as demonstrated by an immunofluorescence technique. Group B streptococci were recovered from blood or liver in six fetuses, including two who had group B streptococci in the amniotic fluid. The study demonstrates an association between the occurrence of group B streptococci in the urine and cervix and late abortions.
对150例有流产迹象的妇女和100例正常妊娠妇女的下泌尿生殖道中B族链球菌的发生情况进行了研究。B族链球菌在流产妇女的尿液(p<0.001)和子宫颈(p<0.01)中出现的频率明显更高。分娩后,85%的尿液中有B族链球菌的患者以及42%的尿液中无B族链球菌的患者(p<0.001)。在胎膜完整的8名妇女中,有3名妇女的羊水培养出B族链球菌,且这些细菌从尿液和宫颈中分离得到。通过免疫荧光技术证实这些细菌被抗体包被。在6例胎儿的血液或肝脏中发现了B族链球菌,其中2例胎儿的羊水中也有B族链球菌。该研究表明尿液和宫颈中B族链球菌的出现与晚期流产之间存在关联。