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成人糖尿病酮症酸中毒危重症患者的评估和管理。

Evaluation and Management of the Critically Ill Adult With Diabetic Ketoacidosis.

机构信息

Department of Emergency Medicine, Brooke Army Medical Center, Fort Sam Houston, Texas.

Department of Emergency Medicine, University of Maryland School of Medicine, Baltimore, Maryland.

出版信息

J Emerg Med. 2020 Sep;59(3):371-383. doi: 10.1016/j.jemermed.2020.06.059. Epub 2020 Aug 4.

Abstract

BACKGROUND

Diabetic ketoacidosis (DKA) is a hyperglycemic emergency that presents commonly to the emergency department. Severe DKA has the potential for significant morbidity and mortality if not recognized early and treated appropriately. It is incumbent on the emergency clinician to be vigilant in the management of these critically ill patients.

OBJECTIVE

This narrative review evaluates the emergency medicine management of the adult patient with severe DKA.

DISCUSSION

DKA is a condition found most commonly in patients with insulin-dependent diabetes, often due to nonadherence with diabetic medications or an inciting event, such as infection or ischemia. The severity of DKA is classified based on the level of acidosis present rather than absolute glucose level. The management of severe DKA involves assessing and treating the inciting event, fluid hydration, insulin, and potassium repletion. Close monitoring is necessary to prevent the complications that can occur.

CONCLUSIONS

DKA is a medical condition that has the potential for significant morbidity and mortality if not recognized and managed appropriately.

摘要

背景

糖尿病酮症酸中毒(DKA)是一种高血糖急症,常见于急诊科。如果不能早期识别和适当治疗,严重的 DKA 有可能导致严重的发病率和死亡率。急诊临床医生有责任警惕地管理这些重症患者。

目的

本综述评价了成人严重 DKA 的急诊医学管理。

讨论

DKA 最常见于依赖胰岛素的糖尿病患者,通常由于不遵守糖尿病药物治疗或诱因事件,如感染或缺血。DKA 的严重程度根据酸中毒的程度而不是绝对血糖水平来分类。严重 DKA 的治疗包括评估和治疗诱因、液体水化、胰岛素和钾补充。需要密切监测以防止发生并发症。

结论

如果不能正确识别和治疗,DKA 是一种具有潜在严重发病率和死亡率的疾病。

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