Advanced Water Management Centre, The University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia; Beijing International Scientific and Technological Cooperation Base of Water Pollution Control Techniques for Antibiotics and Resistance Genes, Beijing Key Laboratory of Aqueous Typical Pollutants Control and Water Quality Safeguard, Department of Municipal and Environmental Engineering, School of Civil Engineering, Beijing Jiaotong University, Beijing 100044, PR China.
Beijing International Scientific and Technological Cooperation Base of Water Pollution Control Techniques for Antibiotics and Resistance Genes, Beijing Key Laboratory of Aqueous Typical Pollutants Control and Water Quality Safeguard, Department of Municipal and Environmental Engineering, School of Civil Engineering, Beijing Jiaotong University, Beijing 100044, PR China.
Environ Int. 2020 Oct;143:105987. doi: 10.1016/j.envint.2020.105987. Epub 2020 Jul 30.
Partial nitritation-Anammox (PN/A) process has been recognized as a sustainable process for biological nitrogen removal. Although various antibiotics have been ubiquitously detected in influent of wastewater treatment plants, little is known whether functional microorganisms in the PN/A process are capable of biodegrading antibiotics. This study aimed to investigate simultaneous nitrogen and antibiotic removal in a lab-scale one-stage PN/A system treating synthetic wastewater containing a widely-used antibiotic, sulfadiazine (SDZ). Results showed that maximum total nitrogen (TN) removal efficiency of 86.1% and SDZ removal efficiency of 95.1% could be achieved when treating 5 mg/L SDZ under DO conditions of 0.5-0.6 mg/L. Compared to anammox bacteria, ammonia-oxidizing bacteria (AOB) made a major contribution to SDZ degradation through their cometabolic pathway. A strong correlation between amoA gene and SDZ removal efficiency was found (p < 0.01). In addition, the degradation products of SDZ did not exhibit any inhibitory effects on Escherichia coli. The findings suggest that it is promising to apply the PN/A process to simultaneously remove antibiotics and nitrogen from contaminated wastewater.
部分亚硝化-厌氧氨氧化（PN/A）工艺已被认为是一种可持续的生物脱氮工艺。尽管各种抗生素已在污水处理厂的进水口被广泛检测到，但对于 PN/A 工艺中的功能微生物是否能够生物降解抗生素，人们知之甚少。本研究旨在考察在一个实验室规模的单级 PN/A 系统中同时去除氮和抗生素的能力，该系统处理含有一种广泛使用的抗生素磺胺嘧啶（SDZ）的合成废水。结果表明，在 DO 为 0.5-0.6mg/L 的条件下，处理 5mg/L 的 SDZ 时，最大总氮（TN）去除效率可达 86.1%，SDZ 去除效率可达 95.1%。与厌氧氨氧化菌相比，氨氧化菌（AOB）通过共代谢途径对 SDZ 的降解做出了重大贡献。amoA 基因与 SDZ 去除效率之间存在很强的相关性（p<0.01）。此外，SDZ 的降解产物对大肠杆菌没有表现出任何抑制作用。研究结果表明，PN/A 工艺有望同时从受污染废水中去除抗生素和氮。
