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急性心肌梗死后第一年的后续住院治疗与初级门诊服务利用情况以及长期死亡率之间的关联。

Associations between Subsequent Hospitalizations and Primary Ambulatory Services Utilization within the First Year after Acute Myocardial Infarction and Long-Term Mortality.

作者信息

Plakht Ygal, Greenberg Dan, Gilutz Harel, Arbelle Jonathan Eli, Shiyovich Arthur

机构信息

Department of Nursing, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva 8410501, Israel.

Department of Emergency Medicine, Soroka University Medical Center, Beer-Sheva 8410501, Israel.

出版信息

J Clin Med. 2020 Aug 5;9(8):2528. doi: 10.3390/jcm9082528.

DOI:10.3390/jcm9082528
PMID:32764490
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7464321/
Abstract

Healthcare resource utilization peaks throughout the first year following acute myocardial infarction (AMI). Data linking the former and outcomes are sparse. We evaluated the associations between subsequent length of in-hospital stay (SLOS) and primary ambulatory visits (PAV) within the first year after AMI and long-term mortality. This retrospective analysis included patients who were discharged following an AMI. Study groups: low (0-1 days), intermediate (2-7) and high (≥8 days) SLOS; low (<10) and high (≥10 visits) PAV, throughout the first post-AMI year. All-cause mortality was set as the primary outcome. Overall, 8112 patients were included: 55.2%, 23.4% and 21.4% in low, intermediate and high SLOS groups respectively; 26.0% and 74.0% in low and high-PAV groups. Throughout the follow-up period (up to 18 years), 49.6% patients died. Multivariable analysis showed that an increased SLOS (Hazard ratio (HR) = 1.313 and HR = 1.714 for intermediate and high vs. low groups respectively) and a reduced number of PAV (HR = 1.24 for low vs. high groups) were independently associated with an increased risk for mortality ( < 0.001 for each). Long-term mortality following AMI is associated with high hospital and low primary ambulatory services utilization throughout the first-year post-discharge. Measures focusing on patients with increased SLOS and reduced PAV should be considered to improve patient outcomes.

摘要

在急性心肌梗死(AMI)后的第一年,医疗资源利用率达到峰值。将前者与预后相关联的数据很少。我们评估了AMI后第一年住院时间(SLOS)和初级门诊就诊次数(PAV)与长期死亡率之间的关联。这项回顾性分析纳入了AMI后出院的患者。研究分组:SLOS低(0 - 1天)、中(2 - 7天)和高(≥8天);AMI后第一年PAV低(<10次)和高(≥10次)。全因死亡率作为主要结局。总体而言,纳入了8112例患者:SLOS低、中、高组分别占55.2%、23.4%和21.4%;PAV低和高组分别占26.0%和74.0%。在整个随访期(长达18年),49.6%的患者死亡。多变量分析显示,SLOS增加(中、高组与低组相比,风险比(HR)分别为1.313和1.714)以及PAV次数减少(低组与高组相比,HR = 1.24)与死亡风险增加独立相关(每组P < 0.001)。AMI后的长期死亡率与出院后第一年高住院率和低初级门诊服务利用率相关。应考虑针对SLOS增加和PAV减少的患者采取措施以改善患者预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4c8/7464321/1debc1795a2a/jcm-09-02528-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4c8/7464321/1debc1795a2a/jcm-09-02528-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c4c8/7464321/1debc1795a2a/jcm-09-02528-g001.jpg

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本文引用的文献

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Isr Med Assoc J. 2020 May;22(5):303-309.
2
Association Between Subsequent Hospitalizations and Recurrent Acute Myocardial Infarction Within 1 Year After Acute Myocardial Infarction.急性心肌梗死后 1 年内再次住院与复发性急性心肌梗死的关系。
J Am Heart Assoc. 2020 Mar 17;9(6):e014907. doi: 10.1161/JAHA.119.014907. Epub 2020 Mar 14.
3
Temporal trends in healthcare resource utilization and costs following acute myocardial infarction.
急性心肌梗死患者医疗资源利用和成本的时间趋势。
Isr J Health Policy Res. 2020 Feb 12;9(1):6. doi: 10.1186/s13584-020-0364-y.
4
Readmission and mortality in patients ≥70 years with acute myocardial infarction or heart failure in the Netherlands: a retrospective cohort study of incidences and changes in risk factors over time.荷兰70岁及以上急性心肌梗死或心力衰竭患者的再入院率和死亡率:一项关于发病率及风险因素随时间变化的回顾性队列研究
Neth Heart J. 2019 Mar;27(3):134-141. doi: 10.1007/s12471-019-1227-4.
5
Healthcare-service utilization and direct costs throughout ten years following acute myocardial infarction: Soroka Acute Myocardial Infarction II (SAMI II) project.急性心肌梗死后十年内的医疗服务利用和直接成本:索罗卡急性心肌梗死 II 期(SAMI II)项目。
Curr Med Res Opin. 2019 Jul;35(7):1257-1263. doi: 10.1080/03007995.2019.1571298. Epub 2019 Feb 21.
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JAMA Netw Open. 2018 Aug 3;1(4):e181079. doi: 10.1001/jamanetworkopen.2018.1079.
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